电针三阴交治疗围绝经期综合征临床观察

目的：客观评价电针三阴交治疗围绝经期综合征的有效性和安全性。方法：将纳入病例随机分为治疗组和对照组。治疗组采用电针双侧三阴交穴，刺激时间30分钟，每周3次，1个月为一疗程，连续治疗3个疗程。对照组采用口服尼尔雌醇，每次2mg，每月2次，连续用药3个月。对已绝经者，第3个月开始加用甲羟孕酮，每天6mg，连用7天。分别于治疗前、治疗1个月、治疗2个月、治疗3个月后，观察血管舒缩症状、精神神经症状以及Kupperman指数评分变化。结果：电针能明显降低困绝经期综合征患者的Kupperman指数评分，改善血管舒缩症状和精神神经症状，且治疗过程中未见严重不良反应。口服西药在Kupperman指数评分上略高于治疗组，但没有统计学意义，改善血管舒缩症状方面不如治疗组，对精神神经症状的改善方面优于治疗组。结论：电针三阴交治疗围绝经期综合征是有效的、安全的。

Clinical observation on therapeutic effect of electroacupuncture at Sanyinjiao (SP 6) on peri-menopausal syndrome

OBJECTIVE: To objectively evaluate the effectiveness and safety of electroacupuncture (EA) at Sanyinjiao (SP 6) for treatment of peri-menopausal syndrome. METHODS: All the patients enrolled were randomly divided into a treatment group and a control group. The treatment group were treated with EA at Sanyinjiao (SP 6) for 3 therapeutic courses, thrice each week, 30 min each time, one month constituting one course. The control group were treated with oral administration of nylestriol for 3 months, 2 mg each time, twice each month. For the menopausal patient, medroxyprogesterone was added from the third month of the treatment for 7 days, 6 mg each day. Changes of vasomotorial symptoms, mental symptoms and scores of Kupperman indexes before and after treatment for 1 month, 2 months and 3 months were investigated. RESULTS: EA could significantly decrease the score of Kupperman indexes, improve vasomotorial symptoms and mental symptoms in the patient of peri-menopausal syndrome with no severe adverse effects. The control group in the score of Kupperman indexes was slightly higher than the treatment group with no significant difference between the two groups, but the treatment group in improvement of the vasomotorial symptoms was better than the control group and in improvement of mental symptoms was not as good as the control group. CONCLUSION: EA at Sanyinjiao (SP 6) is effective and safe for treatment of peri-menopausal syndrome.