Affiliation: | (1) Department of Radiology and Medical Imaging, University of Virginia Health System, Charlottesville, VA 22908, USA;(2) Department of Orthopaedic Surgery, University of Virginia Health System, Charlottesville, VA 22908, USA;(3) Department of Pathology, University of Virginia Health System, Charlottesville, VA 22908, USA;(4) Department of Pediatrics, University of Virginia Health System, Charlottesville, VA 22908, USA; |
Abstract: | Scurvy is a lethal but treatable disease that is rare in industrialized countries. Caused by vitamin C deficiency, it is most prevalent in persons of low socioeconomic status and smokers. Low levels of circulating vitamin C result in poor collagen fiber formation that, in turn, leads to demineralized bones, microfractures, and poor healing. Here we report a case of scurvy in a 5-year-old boy with normal radiographs in whom initial concern for leukemia based upon magnetic resonance imaging and clinical presentation led to a bone marrow biopsy revealing gelatinous transformation. |