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Magnetic resonance imaging appearance of scurvy with gelatinous bone marrow transformation
Authors:Christopher?M.?Brennan,Kristen?A.?Atkins,Colleen?H.?Druzgal,Cree?M.?Gaskin  author-information"  >  author-information__contact u-icon-before"  >  mailto:CMGS@hscmail.mcc.virginia.edu"   title="  CMGS@hscmail.mcc.virginia.edu"   itemprop="  email"   data-track="  click"   data-track-action="  Email author"   data-track-label="  "  >Email author
Affiliation:(1) Department of Radiology and Medical Imaging, University of Virginia Health System, Charlottesville, VA 22908, USA;(2) Department of Orthopaedic Surgery, University of Virginia Health System, Charlottesville, VA 22908, USA;(3) Department of Pathology, University of Virginia Health System, Charlottesville, VA 22908, USA;(4) Department of Pediatrics, University of Virginia Health System, Charlottesville, VA 22908, USA;
Abstract:Scurvy is a lethal but treatable disease that is rare in industrialized countries. Caused by vitamin C deficiency, it is most prevalent in persons of low socioeconomic status and smokers. Low levels of circulating vitamin C result in poor collagen fiber formation that, in turn, leads to demineralized bones, microfractures, and poor healing. Here we report a case of scurvy in a 5-year-old boy with normal radiographs in whom initial concern for leukemia based upon magnetic resonance imaging and clinical presentation led to a bone marrow biopsy revealing gelatinous transformation.
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