2007—2013���Ϻ�����ҽԺ���Ժ�������Ⱦ�������ò����׼���������������

Epidemiological characteristics of viral spectrum detected by throat swab: A consecutive study on children with acute respiratory infections from 2007 to 2013 in Nanxiang Hospital in Shanghai

??Objective To analyze the seasonal variation of viral spectrum detected by throat swab in children with respiratory infections. Methods Totally 4389 throat swab samples were collected weekly at the Pediatric Outpatient Department between 2007 and 2013 in Shanghai Jiading Nanxiang Hospital. Totally 325 cases of influenza A and 128 cases of influenza B viruses??FLU-A??B????67 human metapneumoviruses??HMPV????320 respiratory syncytial viruses??RSV????274 parainfluenza viruses??PIV?? 1-4??105 human enteroviruses??EV????72 human rhinoviruses??HRV????105 coronaviruses??Cov????118 human Boca virus??HBOV?? and 146 human adenoviruses??ADV?? were identified by RT-PCR. Results Viruses were detected in 1526??34.8%?? throat swab samples. FLU-A was detected mostly?? in 7.4%??325/4389?? samples??followed by RSV 7.3%??320/4389???? ADV 3.3%??146/4389????and PIV-1 2.9%??128/4389??. Between 2007 and 2012??the rate of FLU-A detection peaked between August and February-March??and PIV-1 was the most frequently detected PIV??peaking in summer. Conclusion In Shanghai winter is the peak season for viruses such as RSV??FLU-B and HBOV. FLU-A is frequently detected between late summer and winter??peaking in summer. Epidemics of PIV-1 also peak in summer. RSV incidence increases in autumn and peaks in winter??presenting an epidemic phenomena of peaking every other year.