妊娠妇女常量元素和必需微量元素的含量及分析

目的了解现期妊娠妇女体内常量元素钙(Ca)、镁(Mg)、磷(IP)和必需微量元素铁(Fe)、锌(Zn)、铜(Cu)在妊娠三期(孕早、中、晚各期)的含量及变化规律。方法用全自动生化分析仪测定妊娠组157份血样及对照组45份血样的Ca、Mg、IP、Fe、Zn、Cu的含量,统计使用方差分析。结果Ca、Mg、Zn的血清含量随着妊娠期的增加而减少,与对照组相比均有显著性差异(P<0.05)。Fe的血清含量在孕早期升高为(21.4±5.75)μmol/L,孕中、晚期下降分别为(17.6±6.99)μmol/L和(17.3±8.46)μmol/L与对照组(18.5±5.51)μmol/L相比无统计学意义(P>0.05)。Cu的血清含量随着妊娠期的增加而增高,且与对照组有显著性差异(P<0.05)。结论在妊娠过程中,常量元素钙、镁和必需微量元素铜、铁、锌都有明显的变化,提示应定期检测孕妇血清钙、镁、磷、铁、锌、铜水平。并采取相应的防治措施,以提高孕产妇及新生儿的健康水平。

Analysis of sera concentration of macro element and microelement in pregnancy women

Objective To analyze sera concentration of the macro element (Ca, Mg, IP ) and microelement (Fe, Zn, Cu ) in pregnancy women. Methods We collected 157 serum samples from early, middle and late pregnancy women and 45 from healthy volunteers. The 6 biochemical parameters were measured by automatic biochemistry analyzer, and statistically analyzed by one-way ANOVA. Results The serum concentration of Ca, Mg and Zn decreased as pregnant week increased and all the three pregnant groups were significantly less than the control group (all P<0.05). The serum Cu increased as pregnant week increased with significant difference from the control group (P<0.05). The serum Fe increased in early pregnancy group and decreased in middle and late pregnant groups, all without significant difference compared to the control group (P>0.05). Conclusion Significant changes of the sera Ca, Mg, Zn and Cu indicate the necessary of routine examination of the macro element and microelement in pregnancy women, so as to conduct medical intervention to improve health care of the pregnancy women and the neonates.