Perfusion MRI in cerebral infarction |
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Authors: | T Hagen K Bartylla M Stoll U Piepgras |
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Institution: | Abteilung für Neuroradiologie, Radiologische Klinik der Universit?t des Saarlandes, XX Neurologische Klinik der Universit?t des Saarlandes, XX
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Abstract: | Purpose: To investigate the hemodynamic changes in patients with acute cerebral stroke by perfusion MRI.
Materials and methods: In 12 patients with acute stroke in the territory of the middle cerebral artery, perfusion MRI was performed. Peak time,
mean transit time, regional cerebral blood volume and regional cerebral blood flow were calculated in the infarction, the
peri-infarction area and the contralateral hemisphere.
Results: In the infarction the mean blood flow was 29 ml/100 g/min, compared to about 40 ml/100 g/min in the peri-infarction area
and the contralateral hemisphere. In two patients increased cortical blood flow was found in the infarction due to luxury
perfusion. The cerebral blood volume was reduced in the infarction, but significantly increased, to 7.3 ml/100 g, in the peri-infarction
tissue.
Conclusion: Perfusion MRI allows one to differentiate various patterns of perfusion disorders in patients with acute cerebral stroke.
The resulting data may be helpful in describing the pathophysiologic mechanisms of compensation.
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Keywords: | Magnetic resonance imaging • Cerebral blood flow • Cerebral blood volume • Acute cerebral stroke |
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