Antithrombotic and thrombolytic therapy for ischemic stroke |
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Authors: | Curtis Benesch |
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Institution: | (1) Department of Neurology, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Box 681, 14642 Rochester, NY, USA |
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Abstract: | Antithrombotic therapy is the mainstay of treatment for stroke prevention. Multiple antiplatelet agents are now proven options
for patients at risk for stroke, whereas warfarin anticoagulation remains the preferred therapy for most patients with atrial
fibrillation. Recent clinical trials have clarified the role of anticoagulation in acute stroke and in secondary prevention
of noncardioembolic stroke. Intravenous tissue plasminogen activator is the only approved therapy for patients with acute
ischemic stroke. Intra-arterial thrombolysis is emerging as a promising therapy in selected patients. |
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