| 慢性肾衰贫血患者尿促红细胞生成素浓度的变化及意义 |
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| 引用本文： | 刘章锁,李国玲,张明轩,赵志平,刘钟明.慢性肾衰贫血患者尿促红细胞生成素浓度的变化及意义[J].河南医学研究,1992(2). |
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| 作者姓名： | 刘章锁 李国玲 张明轩 赵志平 刘钟明 |
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| 作者单位： | 河南医科大学第一附属医院内科，河南医科大学第一附属医院内科，河南医科大学第一附属医院内科，河南医科大学第一附属医院内科，河南医科大学第一附属医院内科 郑州 450052，郑州 450052，郑州 450052，郑州 450052，郑州 450052 |
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| 基金项目： | 本课题由河南省医学科学院科研基金资助 |
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| 摘 要： | 本实验采用“胎鼠肝细胞体外培养法”测定了40例正常人和75例不同原因贫血患者尿促红细胞生成素(EPO)浓度。结果显示:①慢性肾衰(CRF)贫血组尿 EPO 浓度明显低于正常组(P<0.001);②血液病贫血组尿 EPO 浓度明显高于正常组(P<0.001),且再生障碍性、溶血性贫血患者与其它原因血液病贫血患者比较有显著意义(P<0.002和 P<0.05);③心肺疾患组尿 EPO 浓度也明显高于正常组(P<0.001)。我们认为尿 EPO 浓度测定在诊断 CRF 贫血和鉴别不同原因疾病贫血方面有一定参考意义。
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| 关 键 词： | 尿促红细胞生成素 贫血 慢性肾衰 血液病 |
SIGNIFICANCE AND CHANGES OF THE URINE ERYTHROPOIETIN IN PATIENTS WITH CHRONIC RENAL FAILURE ANEMIA |
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| Liu Zhang-suo,et al.SIGNIFICANCE AND CHANGES OF THE URINE ERYTHROPOIETIN IN PATIENTS WITH CHRONIC RENAL FAILURE ANEMIA[J].Henan Medical Research,1992(2). |
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| Authors: | Liu Zhang-suo |
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| Abstract: | By use of the fetal mouse liver cell culture technique in vivo,urine erythropoietin (EPO)was measured in 75 patients with different causes of anemia and 40 healthy subjects.The re suits showed:comparing to the urine EPO in healthy subjects,chronic renal failure(CRF)anemia group was extremely Iower(P<0. 001).and the patients suffering from anemia of blood diseases and cardiopuimonary diseases groups were much highcr(P<0. 001).Besides these,there was a marked dif- tercnee between aplastic anemia &.hemolytic anemia and other kinds of blood diseases(P<0.002,P <0.05).We concluded that the determination of urine EPO might take important role in diagnosing CRF anemia and distinguishing different kinds of anemia. |
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| Keywords: | Urine erythropoietin Anemia Chronic Renal Failure Blood Disease |
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