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喜炎平注射液治疗小儿轮状病毒肠炎合并心肌损害的疗效观察
引用本文:施长城,张坤明,刘霞,刘素琴,钱汉斌.喜炎平注射液治疗小儿轮状病毒肠炎合并心肌损害的疗效观察[J].中国药房,2011(47):4495-4496.
作者姓名:施长城  张坤明  刘霞  刘素琴  钱汉斌
作者单位:江苏扬州市妇幼保健院,扬州市225002
摘    要:目的:观察喜炎平注射液治疗小儿轮状病毒肠炎合并心肌损害的临床疗效。方法:将80例患者随机均分为对照组和观察组,观察组给予喜炎平注射液(5mg·kg-1d-1)并对症补液治疗;对照组给予利巴韦林注射液(10~15mg·kg-1·d-1)并对症补液治疗。2组病例均在初治和治疗5~7d后检查和复查心肌酶谱水平。结果:治疗后2组心肌酶谱水平均较治疗前有显著下降(P<0.05);组间比较除乳酸脱氢酶外,均有显著性差异(P<0.05);观察组总有效率为95%,对照组为77.5%,2组比较有显著性差异(P<0.05)。结论:喜炎平注射液治疗小儿轮状病毒肠炎合并心肌损害有明显疗效,且未见明显不良反应。

关 键 词:喜炎平注射液  轮状病毒肠炎  心肌损害

Efficacy Observation of Xiyanping Injection in the Treatment of Infantile Rotavirus Enteritis Complicating with Cardiac Damage
SHI Chang-cheng,ZHANG Kun-ming,LIU Xia,LIU Su-qin,QIAN Han-bin.Efficacy Observation of Xiyanping Injection in the Treatment of Infantile Rotavirus Enteritis Complicating with Cardiac Damage[J].China Pharmacy,2011(47):4495-4496.
Authors:SHI Chang-cheng  ZHANG Kun-ming  LIU Xia  LIU Su-qin  QIAN Han-bin
Institution:(Yangzhou Municipal Maternal and Child Health Hospital of Jiangsu Province, Yangzhou 225002, China)
Abstract:OBJECTIVE: To observe the clinical efficacy of Xiyanping injection in the treatment of infantile rotavirus enteritis complicating with cardiac damage. METHODS: 80 children were randomly divided into control group and observation group (40 cases in each group). The patients in observation group were given Xiyanping injection (5 mg·kg·d-1) and symptomatic treatment, and the patients in control group were given Virazole injection(10- 15 mg·kg·d-1) and symptomatic treatment. The cards cardiac enzymes spectrum of 2 groups were checked and rechecked at the beginning of treatment and 5-7 days after treatment. RESULTS: The cards cardiac enzymes spectrum of 2 groups decreased significantly after treatment, compared with before treatment(P〈0.05). There were significant difference between 2 groups, besides LDH (P〈0.05). The total effective rate in the observation group was 95%, while in control group was 77.5%, There was significant difference between the two groups (P〈0.05). CONCLUSION: Xi- yanping injection is significantly effective for infantile rotavirus enteritis complicating with cardiac damage without obvious adverse drug reactions. KEY WORDS Xiyanping injection; Rotavirus enteritis; Cardiac damage
Keywords:Xiyanping injection  Rotavirus enteritis  Cardiac damage
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