| 正交试验优选荆防止痒颗粒提取工艺 |
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| 引用本文： | 廖银根,丁志军,罗美兰,许时贵.正交试验优选荆防止痒颗粒提取工艺[J].中国药房,2011(39):3673-3675. |
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| 作者姓名： | 廖银根 丁志军 罗美兰 许时贵 |
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| 作者单位： | 江西省皮肤病专科医院,南昌市330001 |
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| 基金项目： | 江西省科技计划项目（赣科发计字[2007]189号） |
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| 摘 要： | 目的:研究荆防止痒颗粒的提取工艺。方法:采用正交试验法,以干膏率及苦参碱、氧化苦参碱转移率为指标,考察加水量、提取次数、提取时间对提取工艺的影响。结果:以饮片投料,加12倍量的水,煎煮2次,每次2h为最佳工艺。结论:该工艺稳定、可靠,可为工业生产提供理论依据。
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| 关 键 词： | 荆防止痒颗粒 苦参碱 氧化苦参碱 正交试验 高效液相色谱法 |
Optimization of the Extraction Technology of Jingfang Zhiyang Granules by Orthogonal Test |
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| LIAO Yin-gen,DING Zhi-jun,LUO Mci-lan,XU Shi-gui.Optimization of the Extraction Technology of Jingfang Zhiyang Granules by Orthogonal Test[J].China Pharmacy,2011(39):3673-3675. |
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| Authors: | LIAO Yin-gen DING Zhi-jun LUO Mci-lan XU Shi-gui |
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| Institution: | (Jiangxi Provincial Special Hospital of Skin, Nanchang 330001, China) |
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| Abstract: | OBJECTIVE： To study the extraction procedure for Jingfang zhiyang granules. METHODS： With extract yield and the content of matrine and oxymatrine as indexes, orthogonal test was used to investigate the effect of water amount, extraction times and the time of extraction on extraction technology. RESULTS： The optimum process was as follows： decoction pieces as sample, adding 12 times amount of water, extracting 2 times, 2 hours for each time. CONCLUSION： The extraction process is stable and reliable for industrial production. |
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| Keywords: | Jingfang zhiyang granules Matrine Oxymatrine Orthogonal test HPLC |
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