| 莲芝消炎片的质量标准研究 |
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| 引用本文： | 梁远园,桂蜀华,倪晨.莲芝消炎片的质量标准研究[J].中国药房,2011(39):3716-3717. |
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| 作者姓名： | 梁远园 桂蜀华 倪晨 |
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| 作者单位： | 广州中医药大学新药开发研究中心,广州市510405 |
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| 摘 要： | 目的:建立莲芝消炎片的质量控制标准。方法:采用薄层色谱(TLC)法对莲芝消炎片中穿心莲、山芝麻进行定性鉴别,采用高效液相色谱法对莲芝消炎片中的脱水穿心莲内酯进行含量测定。结果:TLC斑点清晰、分离度好,阴性对照无干扰;脱水穿心莲内酯进样量在0.516～5.16μg范围内与峰面积积分值呈良好线性关系(r=0.9999),平均回收率为98.46%,RSD=2.89%(n=6)。结论:所建标准可用于莲芝消炎片的质量控制。
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| 关 键 词： | 莲芝消炎片 质量标准 脱水穿心莲内酯 高效液相色谱法 薄层色谱法 |
Quality Standards of Lianzhi Xiaoyan Tablets |
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| LIANG Yuan-yuan,GUI Shu-hua,NI Chen.Quality Standards of Lianzhi Xiaoyan Tablets[J].China Pharmacy,2011(39):3716-3717. |
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| Authors: | LIANG Yuan-yuan GUI Shu-hua NI Chen |
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| Institution: | (Center for New Drugs Development and Research, Guangzhou University of Traditional Chinese Medicine, Guangzhou 510405, China) |
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| Abstract: | OBJECTIVE ： To establish the quality standard of Lianzhi xiaoyan tablets. METHODS ： TLC was used to identify Andrographis paniculata and Radix helicteris. HPLC method was used to determine the content of dehydroandrographolide in Lianzhi xiaoyan tablets. RESULTS：TLC spots were clear and well-separated without interference from negative samples. The linear range of dehydroandrographolide was 0.516-5.16 μg（r=0.999 9） with an average recovery of 98.46% （RSD=2.89%, n=6）. CONCLUSION. Established standard is simple and accurate for the quality control of Lianzhi xiaoyan tablets. |
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| Keywords: | Lianzhi xiaoyan tablets Quality standard Dehydroandrographolide HPLC TLC |
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