| 复方夏枯草降压颗粒的质量标准研究 |
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| 引用本文： | 饶友义,倪友洪.复方夏枯草降压颗粒的质量标准研究[J].中国药房,2011(47):4475-4477. |
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| 作者姓名： | 饶友义 倪友洪 |
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| 作者单位： | [1]四川绵阳市中心医院药剂科,绵阳市621000 [2]成都华大爱康医药技术有限公司,成都市610041 |
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| 摘 要： | 目的:建立复方夏枯草降压颗粒的质量标准。方法:采用薄层色谱(TLC)法对制剂中夏枯草、白芍、槐角进行定性鉴别;用高效液相色谱法测定制剂中芍药苷的含量。结果:TLC法快速、灵敏,斑点清晰,分离度好,阴性无干扰;芍药苷检测浓度在8.848～442.400μg·mL-1范围内与峰面积积分值呈良好的线性关系(r=0.9999,n=7);平均回收率为100.11%,RSD=1.10%(n=6)。结论:所建标准可用于复方夏枯草降压颗粒的质量控制。
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| 关 键 词： | 复方夏枯草降压颗粒 薄层色谱法 芍药苷 高效液相色谱法 质量控制 |
Quality Standards of Compound Xiakucao Jiangya Granules |
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| RAO You-yiDept. of Pharmacy,Mianyang Central Hospital of Sichuan Province,Mianyang,China NI You-hong.Quality Standards of Compound Xiakucao Jiangya Granules[J].China Pharmacy,2011(47):4475-4477. |
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| Authors: | RAO You-yiDept of Pharmacy Mianyang Central Hospital of Sichuan Province Mianyang China NI You-hong |
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| Institution: | RAO You-yi(Dept. of Pharmacy, Mianyang Central Hospital of Sichuan Province, Mianyang 621000, China) NI You-hong(Chengdu Acon Pharm-tec Co., Ltd., Chengdu 610041, China) |
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| Abstract: | OBJECTIVE： To establish the quality standard of Compound xiakucao jiangya granules. METHODS： Prunella vulgaris, Paevnia lactiflora, Sophora japonica were identified by TLC, and the content of peoniflorin in the preparation was determined by HPLC. RESULTS： TLC was rapid and sensitive, and TLC spots were clear and well-separated without interference from negative substance. The linear range of peoniflorin was 8.848-442.400μg. mL-1（r=0.999 9, n=7） with an average recovery of 100.11% （RSD =1.10 %, n = 6）. CONCLUSION： Established standard can be used for the quality control of Compound xiakucao ji- angya granules. |
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| Keywords: | Compound xiakucao jiangya granules TLC Peoniflorin HPLC Quality control |
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