| 左旋门冬酰胺酶致脑梗死1例分析 |
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| 引用本文： | 衣淑珍,王凯. 左旋门冬酰胺酶致脑梗死1例分析[J]. 中国药房, 2011, 0(48): 4590-4591 |
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| 作者姓名： | 衣淑珍 王凯 |
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| 作者单位： | [1]海军总医院药剂科,北京市100048 [2]海军总医院儿科,北京市100048 |
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| 摘 要： | 目的:提示临床重视左旋门冬酰胺酶致脑梗死的不良反应。方法:报道分析1例7岁急性淋巴细胞白血病患儿使用左旋门冬酰胺酶强化治疗后,同期CT和MRI提示脑血管梗死的病例。检索国内文献未见这方面的报道。结果与结论:国内患者亦可发生左旋门冬酰胺酶诱导的血栓栓塞,栓塞引起的临床症状经及时对症治疗是可逆的。
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| 关 键 词： | 左旋门冬酰胺酶 脑血管梗死 药品不良反应 |
Analysis of 1 Case of Cerebral Infarction Induced by L-asparaginase |
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| YI Shu-zhenDept. of Pharmacy,Navy General Hospital,Beijing,China WANG Kai. Analysis of 1 Case of Cerebral Infarction Induced by L-asparaginase[J]. China Pharmacy, 2011, 0(48): 4590-4591 |
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| Authors: | YI Shu-zhenDept. of Pharmacy Navy General Hospital Beijing China WANG Kai |
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| Affiliation: | YI Shu-zhen(Dept. of Pharmacy, Navy General Hospital, Beijing 100048, China) WANG Kai(Dept. of Pediatrics, Navy General Hospital, Beijing 100048, China) |
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| Abstract: | To prompt medical staff to pay attention to adverse drug reactions due to cerebral infarction induced by L-asparaginase. METHODS： One 7-year-old child with acute lymphoblastic leukemia with intensive treatment of L-asparaginase was reported and analyzed, compared CT and MRI prompting cerebrovascular infarction cases. RESULTS ＆ CONCLUSIONS： Do- mestic literatures were retrieved, while none of them regarded it. Domestic patients can also suffer from L-asparaginase-induced thrombosis. Clinical svmotoms caused by thrombosis are reversible after svmmomatic treatment_ |
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| Keywords: | L-asparaginase Cerebral infarction Adverse drug reactions |
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