伴有癫痫发作的颅内占位性病变520例临床分析

目的 了解各种颅内占位性病变的癫痫发生率，癫痫与病变性质部位的关系及治疗效果等。方法 对10年来的收治520例伴有癫痫发作的颅内占位性病变进行综合分析。结果 各种颅内占位性病变(不含血肿)均可引起癫痫发作，其发生率为27．9％，其中“良性”占位所引起的癫痫占70．2％，胶质瘤与转移瘤所引起的占29．8％，脑膜瘤和胶质瘤所引起的癫痫，分别占总数的36．2％和26．5％。在单一病种中，出现癫痫机率最高为脑囊虫病(88．2％)，其次AVM(80％)，最低的是垂体瘤(占2．1％)。病灶清除手术的治愈率为83．7％。结论 颅内占位性病变的癫痫发生率与病变的性质、部位有关，手术治疗效果良好。

Clinical analysis of 520 cases of intracranial spac-occupying lesion accompanying epileptic attack

Objective To identify the incidence rate of epileptic attack in intracranial space-occupying lesions,the relation between epilepsy and region?property of the lesion,the treatment outcome.Methods A retrospective analysis of 520 cases of intracrainal space-occupying lesion accompanying epilepsy attack in ten years was undertaken.Results Nearly every category of intracranial space-occupying lesion (except hematoma) can induce epileptic attack,the overall incidence was 27.9%,the benign lesion accounted for 70.2% incidence of epilepsy,while glioma and metastases accounted for 29.8%.Meningoma and glioma accounted for 36.2% and 26.5% respectively.For single category,cerebral cysticercosis has the highest incidence of epilepsy (88.2%),the second was AVM(80%),the lowest incidence was hypophysoma(21%),the curative ratio of operation was 83.7%.Conclusions The incidence of epilepsy in the intracranial space-occupying lesions are related to its region and property,the results of surgical treatment are good.