Results for five sets of forensic genetic markers studied in a Greek population sample |
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| Institution: | 1. Section of Forensic Genetics, Department of Forensic Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Frederik V’s Vej 11, DK-2100 Copenhagen, Denmark;2. DNA Analysis Laboratory, Athens Legal Medicine Department, Ministry of Justice, Athens, Greece;1. Department of Public Health Sciences and Pediatrics, University of Turin, Italy;2. Department of Forensic Molecular Biology, Erasmus MC University Medical Center Rotterdam, The Netherlands;3. Office of the Chief Forensic Scientist, Victoria Police Forensic Services Department, Macleod, Australia;4. Department of Forensic Genetics, Studio Indagini Mediche e Forensi (SIMEF), Reggio Calabria, Italy;5. Department of Medical and Surgical Sciences, Institute of Legal Medicine, University of Bologna, Italy;6. Department of Biomedical and Surgical Sciences, Section of Legal Medicine and Forensic Science, University of Perugia, Italy;7. Dipartimento di Medicina Legale, del Lavoro, Psicologia Medica e Criminologia, Università di Genova, Italy;8. Department of Medical Sciences, University of Turin, Italy;9. HuGeF, Human Genetics Foundation, Turin, Italy;10. Department of Public Health, UOL of Legal Medicine, University of Ferrara, Italy;11. SC Medicina Legale, Università di Modena, Italy;12. Department of Biomedicine and Prevention, University of Rome “Tor Vergata”, Italy;13. ANDROS Day Surgery Clinic, Forensic Genetics Unit, Palermo, Italy;14. SOD Genetics Diagnostics, Forensic Genetics, Azienda Ospedaliera Universitaria Careggi, Florence, Italy;15. Section of Legal Medicine, Università Politecnica Delle Marche, Ancona, Italy;p. Dipartimento di Scienze Biomediche per la Salute, Università degli Studi di Milano, Italy;q. Interdisciplinary Department of Medicine, Section of Legal Medicine, University of Bari, Italy;r. Department of Molecular Medicine, University of Padova, Italy;s. Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Italy;t. Department of Biomedical Sciences and Human Oncology, Medical Genetics Unit, “Aldo Moro” University of Bari, Italy;u. Istituto di Medicina Legale, Università Cattolica del Sacro Cuore, Roma, Italy;v. Department of Biopathology, Medical and Forensic Biotechnologies, University of Palermo, Italy;w. Department of Medicine, Surgery and Health, University of Trieste, Italy;x. Dipartimento di Sanità Pubblica e Medicina di Comunità, Università degli Studi di Verona, Italy;y. Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Italy;1. Department of Forensic Biology, West China School of Basic Science and Forensic Medicine, Sichuan University, Chengdu 610041, Sichuan, China;2. Department of Forensic Analytical Toxicology, West China School of Basic Science and Forensic Medicine, Sichuan University, Chengdu 610041, Sichuan, China;3. The Center for Material Evidence, Tibet Autonomous Region Public Security, Lhasa 850000, Tibet Autonomous Region, China;1. Institute for Medical Research, University of Belgrade, Belgrade, Serbia;2. Center for Forensic and Applied Molecular Genetics, Faculty of Biology, University of Belgrade, Belgrade, Serbia;3. Institute of Forensic Medicine, Clinical Center of Vojvodina, Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia;4. Institute for forensic medicine, criminology and medical deontology, Medical Faculty, University of St. Cyril and Methodius, Skopje, Macedonia;5. Faculty of Mathematics, University of Belgrade, Belgrade, Serbia;6. Institute of History, Belgrade, Serbia;1. Institute of Applied Genetics, Department of Molecular and Medical Genetics, University of North Texas Health Science Center, 3500 Camp Bowie Blvd., Fort Worth, TX, 76107, USA;2. Promega Corporation, 2800 Woods Hollow Rd, Madison, WI, 53711, USA;3. Department of Forensic Science, College of Criminal Justice, Sam Houston State University, 1003 Bowers Blvd., Huntsville, TX, 77341, USA;4. Center of Excellence in Genomic Medicine (CEGMR), King Abdulaziz University, Jeddah, Saudi Arabia;1. Turkish Cypriot DNA Laboratory, Committee on Missing Persons in Cyprus Turkish Cypriot Member Office, Nicosia, North Cyprus;2. Institute of Forensic Science, Istanbul University, Istanbul, Turkey |
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| Abstract: | A population sample of 223 Greek individuals was typed for five sets of forensic genetic markers with the kits NGM SElect?, SNPforID 49plex, DIPplex®, Argus X-12 and PowerPlex® Y23. No significant deviation from Hardy–Weinberg expectations was observed for any of the studied markers after Holm–?idák correction. Statistically significant (P < 0.05) levels of linkage disequilibrium were observed between markers within two of the studied X-chromosome linkage groups. AMOVA analyses of the five sets of markers did not show population structure when the individuals were grouped according to their geographic origin. The Greek population grouped closely to the other European populations measured by FST* distances. The match probability ranged from a value of 1 in 2 × 107 males by using haplotype frequencies of four X-chromosome haplogroups in males to 1 in 1.73 × 1021 individuals for 16 autosomal STRs. |
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| Keywords: | Greek population NGM SElect? Argus X-12 |
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