A commentary on the importance of controlling for medication use within trials on the effects of exercise on depression and anxiety |
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| Institution: | 1. Section of Clinical Biochemistry, University of Verona, Verona, Italy;2. Laboratory of Clinical Chemistry and Hematology, University Hospital of Parma, Italy;3. Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy;4. Institute of Biotechnology, Faculty 2, Brandenburg Technical University, Senftenberg, Germany and Medipan GmbH, Dahlewitz/Berlin, Germany;5. Center for Research in Mountain, Sport and Health (CeRISM), Rovereto, Italy |
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| Abstract: | The aims of this commentary are to (1) identify the potential interactive effects of exercise with anxiety/depression medications, based on mechanistic or observational studies, (2) describe how studies dealt with use of antidepressant or anxiolytic participants' medications in their study design and analyses, based on a narrative review of Randomized Controlled Trials (RCTs), and (3) consider the implications for future research for assessing the use of medications within trials and using this information in analyses. |
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| Keywords: | Antidepressant Anxiolytic Exercise Physical activity Randomized controlled study Cancer |
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