| 造影剂量和注射流率对肝脏CT灌注成像影响的实验研究 |
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| 引用本文： | 范光明,郭启勇,解学乾,陈丽英,于涛,侯阳.造影剂量和注射流率对肝脏CT灌注成像影响的实验研究[J].中国医学影像技术,2005,21(1):14-17. |
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| 作者姓名： | 范光明 郭启勇 解学乾 陈丽英 于涛 侯阳 |
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| 作者单位： | 1. 中国医科大学附属第二医院放射科,辽宁,沈阳,110004
2. 上海市第一人民医院放射科,上海,200080 |
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| 摘 要： | 目的探讨用斜率法进行肝脏CT灌注成像时造影剂量和注射流率对灌注参数的影响。方法分别用0．5、1ml／kg体重的造影剂量和3、5、7、9ml／s的注射流率对6只犬进行肝脏灌注成像，计算肝动脉灌注量(HAP)、门脉灌注量(PVP)和肝动脉灌注指数(HPI)。结果造影剂量为0．5ml／kg体重时，3ml／s流率与其他流率测得的HAP和PVP有显著性差异(P＜0．05)，HPI随着流率的增加而略有下降；造影剂量为1ml／kg体重时，各种流率下的HAP和HPI均无显著性差异(P＞0．05)，PVP先升高后降低。结论用斜率法进行肝脏灌注成像时，造影剂量和注射流率对灌注参数有所影响。
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| 关 键 词： | 体层摄影术，X线计算机 灌注 肝脏 定量 动物，实验 |
| 文章编号： | 1003-3289(2005)01-0014-04 |
| 收稿时间： | 2004/9/15 0:00:00 |
| 修稿时间： | 2004年9月15日 |
Influence of contrast agent's dose and injection rate on hepatic perfusion CT: an experimental study |
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| FAN Guang-ming,GUO Qi-yong,XIE Xue-qian,CHEN Li-ying,YU Tao and HOU Yang.Influence of contrast agent''s dose and injection rate on hepatic perfusion CT: an experimental study[J].Chinese Journal of Medical Imaging Technology,2005,21(1):14-17. |
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| Authors: | FAN Guang-ming GUO Qi-yong XIE Xue-qian CHEN Li-ying YU Tao and HOU Yang |
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| Institution: | Department of Radiology, the Second Affiliated Hospital, China Medical University, Shenyang 110004, China;Department of Radiology, the Second Affiliated Hospital, China Medical University, Shenyang 110004, China;Department of Radiology, the First Hospital of Shanghai, Shanghai 200080, China;Department of Radiology, the Second Affiliated Hospital, China Medical University, Shenyang 110004, China;Department of Radiology, the Second Affiliated Hospital, China Medical University, Shenyang 110004, China;Department of Radiology, the Second Affiliated Hospital, China Medical University, Shenyang 110004, China |
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| Abstract: | Objective To investigate the influence of various doses of contrast agent and injection rates on hepatic perfusion imaging using slope method. Methods Hepatic perfusion CT was performed in 6 dogs with different doses of contrast agent (0.5,1 ml/kg) and different injection rates(3,5,7,9 ml/s). Hepatic arterial perfusion (HAP), portal venous perfusion (PVP) and hepatic perfusion index (HPI) were calculated with special software. Results With the dose of 0.5 ml/kg of body weight, HAP and PVP at the injection rate of 3 ml/s were significantly lower than that of other injection rates ( P < 0.05 ). HPI dropped slightly with increasing injection rate.With the dose of 1 ml/kg of body weight, no significant difference was found in HAP and HPI at different injection rates ( P >0.05). PVP rose at first and then dropped. Conclusion When slope method is used in hepatic perfusion imaging, the dose of contrast agent and injection rate have some influence on hepatic perfusion parameters. |
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| Keywords: | Tomography X-ray computed Perfusion Liver Quantification Animals laboratory |
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