Rasmussen's encephalitis: a role for autoimmune cytotoxic T lymphocytes |
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| Authors: | Bauer Jan Bien Christian G Lassmann Hans |
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| Affiliation: | Brain Research Institute, Division of Neuroimmunology, University of Vienna, Vienna, Austria. |
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| Abstract: | The present review describes advances in Rasmussen's encephalitis (also known as Rasmussen's syndrome), an unihemispheric intractable epileptic disease with persistent inflammation. Specific attention is given to the recent recognition of cytotoxicity by CD8+/granzyme-B-positive T lymphocytes as a new pathogenic mechanism of neuronal damage. |
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