| 了哥王石油醚部位化学成分的分离与鉴定 |
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| 引用本文： | 唐晓芳,董梦羽,许倩,时天然,杨雪钰,殷军,刘志惠. 了哥王石油醚部位化学成分的分离与鉴定[J]. 沈阳药科大学学报, 2021, 0(1): 8-12 |
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| 作者姓名： | 唐晓芳 董梦羽 许倩 时天然 杨雪钰 殷军 刘志惠 |
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| 作者单位： | 1.沈阳药科大学药学院;2.沈阳药科大学中药学院 |
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| 基金项目： | 沈阳药科大学创新创业训练计划资助项目(201910163121)。 |
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| 摘 要： | 目的 对苗药了哥王[Wikstroemia indica(L.)C.A.Mey]石油醚部位中的化学成分进行研究.方法 采用硅胶柱色谱、Sephadex LH-20凝胶柱色谱、中压ODS柱色谱、制备HPLC等多种分离纯化手段,对了哥王乙醇提取后石油醚萃取部位的化学成分进行分离、纯化,通过各化合物的理化性质和波谱数据确定化...
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| 关 键 词： | 了哥王 化学成分 结构鉴定 |
Isolation and identification of chemical constituents from Wikstroemia indica (L.) C.A.Mey |
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| TANG Xiaofang,DONG Mengyu,XU Qian,SHI Tianran,YANG Xueyu,YIN Jun,LIU Zhihui. Isolation and identification of chemical constituents from Wikstroemia indica (L.) C.A.Mey[J]. Journal of Shenyang Pharmaceutical University, 2021, 0(1): 8-12 |
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| Authors: | TANG Xiaofang DONG Mengyu XU Qian SHI Tianran YANG Xueyu YIN Jun LIU Zhihui |
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| Affiliation: | (School of Pharmacy,Shenyang Pharmaceutical University,Shenyang 110016,China;School of Traditional Chinese Materia Medica,Shenyang Pharmaceutical University,Shenyang 110016,China) |
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| Abstract: | Objective To investigate the chemical constituents from petroleum fraction of Wikstroemia indica(L.)C.A.Mey.Methods Chromatographic methods were used for the isolation and purification,including silica gel,ODS,Sephadex LH-20 or preparative HPLC.The structures of isolated compounds were identified by physicochemical properties and spectral data analysis.Results Ten compounds were obtained and elucidated as friedeline(1),daphnelantoxin B(2),daphnolone(3),oleanolic acid(4),3β-acetoxy-27-[(4-hydroxybenzoyl)oxy]olean-12-en-28-oic acid methyl ester(5),1,3,5-trimethoxybenzene(6),daphnelanotoxin A(7),(+)-1,5-diphenyl-3-hydroxy-1-pentanone(8),umbelliferone(9)and benzoic acid(10).Conclusion Compound 5 is isolated from genus Wikstroemia for the first time and compounds 1-4 are obtained from this plant for the first time. |
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| Keywords: | Wikstroemia indica(L.)C.A.Mey chemical constituent structure identification |
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