| 磷霉素钠与加替沙星氯化钠注射液配伍的稳定性考察 |
| |
| 引用本文： | 惠春,林大专,张凌赢,曾宪东,孙莹.磷霉素钠与加替沙星氯化钠注射液配伍的稳定性考察[J].中国药事,2009,23(2):174-176. |
| |
| 作者姓名： | 惠春 林大专 张凌赢 曾宪东 孙莹 |
| |
| 作者单位： | 长春医学高等专科学校,长春,130031 |
| |
| 摘 要： | 目的考察磷霉素钠与加替沙星氯化钠注射液配伍变化,为临床合理用药提供参考依据。方法在室温条件下观察及测定配伍液8h内的pH及外观变化,并用紫外光谱法监测配伍液中加替沙星的图谱和含量变化。结果两药配伍后,在8h内配伍液的pH及外观无明显变化,而配伍液中加替沙星的紫外图谱和含量均有明显变化。结论磷霉素钠不宜和加替沙星氯化钠注射液配伍使用。
|
| 关 键 词： | 磷霉素钠 加替沙星 配伍 稳定性 |
Study on the Compatibility of Fosfomycin Sodium with Gatifloxacin and Sodium Chloride Injection |
| |
| Hui Chun,Lin Dazhuan,Zhang Linying,Zeng Xiandong,Sun Ying.Study on the Compatibility of Fosfomycin Sodium with Gatifloxacin and Sodium Chloride Injection[J].Chinese Pharmaceutical Affairs,2009,23(2):174-176. |
| |
| Authors: | Hui Chun Lin Dazhuan Zhang Linying Zeng Xiandong Sun Ying |
| |
| Institution: | (Chang Chun Medical College, Changchun 130031 ) |
| |
| Abstract: | Objective To observe the compatibility of Chloride Injection, provide reference for clinical rational fosfomycin sodium with Gatifloxacin and Sodium drug use. Methods At room temperature for 8 hours, the content and UV spectra of fosfomycin sodium with Gatifloxacin and Sodium Chloride Injection were determined by UV spectrophotometry and the change in appearance, pH value were observed. Results There were no evident change in pH value and appearance after the mixture, but the content and UV spectra of the gatifloxacin were changed significantly. Conclusions There exists incompatibility between Fosfomycin Sodium for Injection and and Sodium Chloride Injection. |
| |
| Keywords: | Fosfomycin sodium Gatifloxacin compatibility stability |
| 本文献已被 维普 万方数据 等数据库收录！ |
|
