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利培酮与舒必利治疗以阴性症状为主的精神分裂症对照研究
引用本文:刘冬青,邱春英,刘艳荣.利培酮与舒必利治疗以阴性症状为主的精神分裂症对照研究[J].中国民康医学,2003,15(1):15-17.
作者姓名:刘冬青  邱春英  刘艳荣
作者单位:1. 山东省滨州市人民医院精神卫生中心,山东滨州,256613
2. 山东省滨州市旧镇医院,山东滨州,256613
摘    要:目的:探索利培酮对阴性症状为主的精神分裂症的疗效与副反应。方法:对80例以阴性症状为主的精神分裂症住院患,用利培酮与舒必利随机对照,采用阳性与阴性症状量表(PANSS)、阴性症状评定量表(SANS)和临床疗效总评量表(CGI-GI)评定疗效,则反应量表(TESS)评定副作用。结果:利培酮与舒必利疗效相当,而副反应严重程度低于舒必利。结论:利培酮是治疗以阴性症状为主的精神分裂症较理想的药物。

关 键 词:精神分裂症  阴性症状  利培酮  舒必利  治疗
文章编号:1672-0369(2003)01-0015-03
修稿时间:2002年2月4日

A comparative study on Risperidone and sulpiride in treating schizophrenia whose predominant clinical features were negative symptoms
LIU dong-qing,QIU Chun-ying,et al.A comparative study on Risperidone and sulpiride in treating schizophrenia whose predominant clinical features were negative symptoms[J].medical journal of chinese peoples health,2003,15(1):15-17.
Authors:LIU dong-qing  QIU Chun-ying  
Abstract:Objective:To probe into clinical therapy and side effect with risperidone in the treatment of schizophrenia whose predominant clinical features were negative syptoms Method:80 cases of schizophrenia whose predominant clinical features were negative syptoms were randomly assigned to treat with either risperidone or sulpiride Efficacy result were assessed by PANSS,SANS,CGI-GI,and side effects by TESS Results:The effective rates of this two groups were similar The serious degree of side effect was lower in risperidone group than that of sulpiride Conclusion:Risperidone is preferred as an ideal agent in the treatment of schizophrenia whose predominant clinical features were negative symptoms
Keywords:Schizophrenia  Negative  symptoms  Risperidone  Sulpiride
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