浙江地区2型糖尿病危险因素分析

目的:探讨浙江地区2型糖尿病发病的潜在危险因素,以便科学有效地预防糖尿病发生。方法:通过对浙江省人民医院18岁～83岁的642例2型糖尿病住院患者采用非条件Logistic回归方法分析糖尿病的危险因素。结果:单因素分析显示腰臀围比≥1.3、BMI≥23.8 kg/m2、吸烟史、饮酒史、家族史、高血清总胆固醇(TC)、高血清甘油三酯(TG)、高水平低密度脂蛋白(LDL)、高水平空腹胰岛素、高血尿酸和高血压可能是2型糖尿病的危险因素。经多因素非条件Lo-gistic回归分析显示腰臀围比(OR=2.203),甘油三酯(OR=1.223),低密度脂蛋白(OR=1.273),高血压(OR=1.672),家族史(OR=2.570)是2型糖尿病的主要危险因素。结论:本研究显示肥胖、高血脂、高血压和家族史是2型糖尿病的独立危险因素。

Study on the risk factors of type 2 diabetes in Chinese people in Zhejiang

Objective:To explore the risk factors for type2 diabetes mellitus in Zhejiang,so as to scientifically prevent the incidence of diabetes mellitus.Methods: On the basis of the epidemiological survey of 642 diabetic patients(18 to 83 years) in Zhejiang Provincial People′s Hospital,the relationship between risk factors and type 2 diabetes mellitus was analyzed by unconditional multivariate Logistic regression on the statistical package for the Social Sciences.Results: Univariate analysis showed that waist-hip ratio ≥ 1.3,BMI≥23.8 kg/m2,smoking,drinking,high total cholesterol(TC),high serum triglyceride(TG),high levels of low density lipoprotein(LDL),high levels of fasting insulin,high blood pressure and high serum uric acid may be risk factors for type 2 diabetes.Multivariate non-conditional Logistic regression analysis showed that waist to hip ratio(OR=2.203),triglycerides(OR=1.223),low density lipoprotein(OR=1.273),hypertension(OR=1.672),family history(OR=2.570) were the major risk factors for type 2 diabetes.Conclusion: This study demonstrated obesity,high cholesterol,hypertension,family history were independent risk factors for type 2 diabetes.