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电视胸腔镜与胸骨劈开行胸腺扩大切除治疗重症肌无力的研究
引用本文:吴昊,邓兴明,麻晓红. 电视胸腔镜与胸骨劈开行胸腺扩大切除治疗重症肌无力的研究[J]. 罕少疾病杂志, 2010, 17(4): 7-10. DOI: 10.3969/j.issn.1009-3257.2010.04.002
作者姓名:吴昊  邓兴明  麻晓红
作者单位:北京大学深圳医院胸外科,深圳,518036
摘    要:目的传统胸骨正中劈开与电视胸腔镜手术(VATS)下行胸腺扩大切除术治疗重症肌无力(MG)的临床疗效比较。探讨VATS治疗重症肌无力的临床应用价值。方法将两组患者分别通过胸骨正中劈开方式和VATS行胸腺完整切除和前纵隔脂肪组织清除术来治疗MG,比较2组患者在手术时间、术中出血量、术后胸管放置时间、术后住院时间、术后发生并发症和疗效等方面的异同。结果 VATS组手术时间(90.5±11.1)min、术中出血量(103.1±8.5)mL、术后胸管放置(2.6±0.6)d、术后住院(5.2±2.4)d等优于开胸组(92.3±12.3)min、(206.1±28.2)mL、(5.6±1.2)d、(9.6±3.1)d;VATS组有l例术中诊断为恶性胸腺瘤改为正中开胸手术,开胸组有2例并发重症肌无力危象,两组围术期均无临床死亡。术后全部患者得到随访,VATS组和开胸组术后缓解好转率均为75.0%。结论 VATS下行胸腺扩大切除术是安全、可行的,具有创伤小、恢复快和疗效可靠等优点。是手术治疗重症肌无力的理想方式。

关 键 词:重症肌无力  电视胸腔镜手术  胸骨部分劈开

Comparison of video-assisted thoracoscopic surgery and thymectomy in the treatment of myasthenia gravis
WU Hao,DENG Xing-ming,MA Xiao-hong. Comparison of video-assisted thoracoscopic surgery and thymectomy in the treatment of myasthenia gravis[J]. Journal of Rare and Uncommon Diseases, 2010, 17(4): 7-10. DOI: 10.3969/j.issn.1009-3257.2010.04.002
Authors:WU Hao  DENG Xing-ming  MA Xiao-hong
Affiliation:WU Hao,DENG Xing-ming,MA Xiao-hong.Department of Thoracic Surgery,Peking University ShenZhen Hospital,ShenZhen 518036,China
Abstract:Objective To investigate the value of video-assisted thoracoscopic surgery(VATS)by comparing the clinic efect of thymectomy and VATS in the treatment of myasthenia gravis(MG).Methods 28 patients who were confirmed to be MG preoperatively from July 2001 to March 2010 were divided into thoracotomy group(12 cases) and VATS group(16 cases).Thymectomy and dissection of all fat tissue anterior to pericardium were performed in both groups.To compare the operative time,blood loss during operation,the time of postop...
Keywords:myasthenia gravis  thoracoscopy  thymectomy  
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