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在慢性无症状乙肝病毒感染者中检测各类核心抗体的意义
引用本文:卢桥生,骆抗先,林汝洪. 在慢性无症状乙肝病毒感染者中检测各类核心抗体的意义[J]. 南方医科大学学报, 1988, 0(3)
作者姓名:卢桥生  骆抗先  林汝洪
作者单位:第一军医大学第一附属医院传染病科(卢桥生,骆抗先),第一军医大学第一附属医院传染病科(林汝洪)
摘    要:总抗-HBc均阳性的慢性无症状乙肝病毒感染者108例,在肝活检的同时,作了血清学检测。结果表明:在血清HBV DNA阴性和肝内HBcAg阴性病例中,与阳性病例相比IgA与IgM抗-HBc检出率较高,但相差不显著;总抗-HBc滴度在肝HBcAg阴性病例中显著增高.总抗-HBc滴度与肝组织炎症活动程度平行,但相差不显著;IgA与IgM抗-HBc检出率则与之密切相关,在IgA与IgM抗-HBc阳性的病例中,肝组织常有肝炎病变。

关 键 词:乙型肝炎病毒  慢性无症状乙肝病毒感染  乙肝核心抗体  免疫球蛋白M  免疫球蛋白A

Significance of various classes of anti-HBc in cases with chronic asymptomatic HBV infection
Lu Qiaosen,et al. Significance of various classes of anti-HBc in cases with chronic asymptomatic HBV infection[J]. Journal of Southern Medical University, 1988, 0(3)
Authors:Lu Qiaosen  et al
Abstract:Liver biops and serological investigations were performed in 108 cases with chronic asymptomatic HBV infection which were total anti-HBc positive. The results showed that the prevalence of IgA and IgM anti-HBc was higher in serum HBV DNA (-) cases than in positive cases, but the differences were ont significant; the serological titer of total anti-HBc was sinificantly higher in liver HBcAg (-)cases. The prevalence of IgA and IgM anti-HBc was closely associated with the liver histology, and the serum anti-HBc titer was also associated, but not so sigificantly.
Keywords:hepatitis B virus  chronic asymptomatic HBV infection  hepatitis B antibodies  IgA  IgM
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