| 在慢性无症状乙肝病毒感染者中检测各类核心抗体的意义 |
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| 引用本文： | 卢桥生,骆抗先,林汝洪.在慢性无症状乙肝病毒感染者中检测各类核心抗体的意义[J].南方医科大学学报,1988(3). |
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| 作者姓名： | 卢桥生 骆抗先 林汝洪 |
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| 作者单位： | 第一军医大学第一附属医院传染病科
(卢桥生，骆抗先)，第一军医大学第一附属医院传染病科(林汝洪) |
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| 摘 要： | 总抗-HBc均阳性的慢性无症状乙肝病毒感染者108例,在肝活检的同时,作了血清学检测。结果表明:在血清HBV DNA阴性和肝内HBcAg阴性病例中,与阳性病例相比IgA与IgM抗-HBc检出率较高,但相差不显著;总抗-HBc滴度在肝HBcAg阴性病例中显著增高.总抗-HBc滴度与肝组织炎症活动程度平行,但相差不显著;IgA与IgM抗-HBc检出率则与之密切相关,在IgA与IgM抗-HBc阳性的病例中,肝组织常有肝炎病变。
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| 关 键 词： | 乙型肝炎病毒 慢性无症状乙肝病毒感染 乙肝核心抗体 免疫球蛋白M 免疫球蛋白A |
Significance of various classes of anti-HBc in cases with chronic asymptomatic HBV infection |
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| Lu Qiaosen,et al.Significance of various classes of anti-HBc in cases with chronic asymptomatic HBV infection[J].Journal of Southern Medical University,1988(3). |
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| Authors: | Lu Qiaosen |
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| Abstract: | Liver biops and serological investigations were performed in 108 cases with chronic asymptomatic HBV infection which were total anti-HBc positive. The results showed that the prevalence of IgA and IgM anti-HBc was higher in serum HBV DNA (-) cases than in positive cases, but the differences were ont significant; the serological titer of total anti-HBc was sinificantly higher in liver HBcAg (-)cases. The prevalence of IgA and IgM anti-HBc was closely associated with the liver histology, and the serum anti-HBc titer was also associated, but not so sigificantly. |
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| Keywords: | hepatitis B virus chronic asymptomatic HBV infection hepatitis B antibodies IgA IgM |
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