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重症SARS的临床治疗及疗效分析
引用本文:张复春,尹炽标,王健,陈燕清,施海燕,洪文昕,唐小平.重症SARS的临床治疗及疗效分析[J].热带医学杂志,2003,3(3):275-278.
作者姓名:张复春  尹炽标  王健  陈燕清  施海燕  洪文昕  唐小平
作者单位:广州市第八人民医院感染科,广州,510060
基金项目:广州市重大科技攻关项目基金(No.2003Z1-E0011)资助。
摘    要:目的:探讨SARS的临床特征及治疗方法。方法:对54例重症SARS患进行回顾性分析。结果:54例患均有高热、进行性呼吸困难和肺部阴影。大多数患ALT、AST及LDH升高。肺部和免疫系统是病毒主要作用的靶器官。治疗以综合支持对症为主,及时应用无创正压通气和大剂量糖皮质激素治疗有较好疗效。结论:综合支持治疗对降低重症SARS的病死率有重要意义。

关 键 词:严重急性呼吸道综合征  治疗  回顾性研究
文章编号:1672-3619(2003)03-0275-04
修稿时间:2003年4月23日

Clinical Analysis and Therapy of Severe Acute Respiratory Syndrome
ZHANG Fu chun,YIN Chi biao,WANG Jian,CHEN Yan qing,SHI Hai yan,HONG Wen xin,TANG Xiao ping.Clinical Analysis and Therapy of Severe Acute Respiratory Syndrome[J].Journal Of Tropical Medicine,2003,3(3):275-278.
Authors:ZHANG Fu chun  YIN Chi biao  WANG Jian  CHEN Yan qing  SHI Hai yan  HONG Wen xin  TANG Xiao ping
Abstract:Objective To investigate the clinical features and management of critical severe acute respiratory syndrome (SARS ). Methods 54 patients with critical SARS were studied retrospectively. Results All patients manifest high fever and followed by progressive dyspnoea and appearance of lung field shadows in X rays findings. Serum ALT, AST and LDH levels were elevated in most patients. Lungs and immune system were main target organs attacked by the virus. General combination therapy was taken for treating the patients. Continual positive airway pressure (CPAP) and glucocorticoid treatments were effective for control of the disease. Conclusion Comprehensive supportive management is of paramount importance in lowering the mortality of patients with critical SARS.
Keywords:severe acute respiratory syndrome(SARS)  therapy  retrospective studies
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