| 胃灵散质量标准研究 |
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| 引用本文： | 赵昕,张治国,郑家富. 胃灵散质量标准研究[J]. 时珍国医国药, 2001, 12(5): 408-409 |
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| 作者姓名： | 赵昕 张治国 郑家富 |
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| 作者单位： | 中国人民解放军沈阳军区联勤部药品检验所, |
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| 摘 要： | 目的建立胃灵散的质量标准。方法采用TLC法对胃灵散中的延胡索、甘草进行了定性鉴别。并用HPLC法对制剂中的白芍所含芍药苷进行了含量测定。ODS分析色谱柱(4mm×250mm，7μm)，流动相甲醇-冰醋酸-水(30∶1∶69)，流速1.0ml/min，检测波长230nm。结果胃灵散中的延胡索乙素、甘草酸铵与其它成分分离良好。高效液相色谱法(HPLC)测定芍药苷、可达基线分离，芍药苷对照品在0.35～1.75μg
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| 关 键 词： | 胃灵散 薄层色谱法 高效液相色谱法 芍药苷 中药 质量标准 |
| 文章编号： | 1008-0805(2001)05-0408-01 |
| 修稿时间： | 2000-12-28 |
Study on the QualityControl of Weiling Powder |
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| ZHAO Xin,ZHANG Zhi-guo,ZHENG Jia-fu. Study on the QualityControl of Weiling Powder[J]. Lishizhen Medicine and Materia Medica Research, 2001, 12(5): 408-409 |
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| Authors: | ZHAO Xin ZHANG Zhi-guo ZHENG Jia-fu |
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| Abstract: | Objective:To develop the quality control of Weiling powder. Methods:Corydalis yanhusuo W. T. Wang and Glycyrrhizae uralensis Fisch in Weiling powder were identified by TLC, and paeoniflorin in Weiling powder separated and determined by HPLC. The chromatographic conditions were as follows:ODS analytic chromatographic column (4.6 mm×250 mm, 7 μm), the mobile phase consisted of methanol-water-acetic acid (30∶1∶69), at a rate of 1.0 ml/min. The wavelength for detection was 230 nm. Results: The standard curves of paeoniflorin was linear in the concentration range of 0.35～1.75 μg*ml-1. The average recovery was 98.8%.(n=5, RSD 0.86%). Conclusion:This method was sensitive, quick and accurate for the quality control of this preparation. |
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| Keywords: | Weiling powder TLC HPLC Paeoniflorin |
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