ALA—PDT治疗男性尿道口尖锐湿疣的疗效观察 |
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引用本文: | 袁艳霞,徐春兴,田婷.ALA—PDT治疗男性尿道口尖锐湿疣的疗效观察[J].中国现代医生,2012,50(2):141-142. |
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作者姓名: | 袁艳霞 徐春兴 田婷 |
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作者单位: | 江苏省常州市第一人民医院皮肤性病科,江苏常州,213000 |
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摘 要: | 目的观察外用氨基酮戊酸光动力疗法(ALA—PDT)治疗男性尿道口尖锐湿疣的疗效和安全性。方法将72例男性尿道口尖锐湿疣患者随机分为ALA—PDT治疗组和CO2激光治疗对照组,每周治疗1次,不超过3次。末次治疗后1周进行疗效评价,随访12周观察皮疹复发情况及不良反应。结果末次治疗后1周,治疗组和对照组临床痊愈率均为100%(P〉0.05),治疗组复发率(11.1%)显著低于对照组(41.7%)(P〈0.01)。治疗组2例患者局部出现浅表糜烂,所有患者无瘢痕形成;对照组11例出现不同程度的瘢痕形成。结论外用ALA—PDT治疗男性尿道口尖锐湿疣治愈率高、复发率低、安全性好。
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关 键 词: | 5-氨基酮戊酸 光动力疗法 尖锐湿疣 尿道口 |
Clinical observation of ALA-PDT in the treatment of urethal condyloma acuminatum |
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Authors: | YUAN Yanxia XU Chunxing TIAN Ting |
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Institution: | Department of Dermatology and Venereology,the First People’s Hospital of Changzhou,Changzhou 213000,China |
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Abstract: | Objective To investigate the clinical efficacy and safety of 5-aminolevuinic acid photodynamic therapy(ALA-PDT) in the treatment of urethal condyloma acuminatum.Methods Seventy-two male patients with urethal condyloma acuminatum were randomly divided into ALA-PDT group and CO2 laser group.The treatment was repeated weekly and no more than 3 times.All patients were followed up for 12 weeks.The therapeutic effect and safty were evaluated.Results The cure rate were 100% of two groups at 1 week after the last treatment,and the recurrent rate of ALA-PDT group(11.1%) was significantly lower than that of the control group(41.7%)(P<0.01).2 patients in treatment group had superficial erosion,11 patients in control group had scar.Conclusion ALA-PDT is an effective and safe therapy with lower recurrence for the treatment of urethal condyloma acuminatum. |
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Keywords: | Aminolevuinic acid Photodynamic therapy Condyloma acuminatum Urethra |
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