早期持续护理干预对喉癌术后气管切开患者放疗不良反应及依从性的影响

目的：探讨早期持续护理干预对喉癌术后气管切开患者在调强放疗期间放疗不良反应发生率及治疗依从性的影响。方法：将72例喉癌术后气管切开患者按随机数字法分为观察组和对照组，观察组36例患者在接受常规治疗的基础上,给予早期持续护理干预，对照组36例患者接受常规护理。比较两组患者在调强放疗过程中口干、口腔黏膜炎、吞咽痛和白细胞计数等不良反应发生率及放疗依从性。结果：观察组口腔黏膜炎、吞咽痛和白细胞计数放疗不良反应率较对照组低，差异有统计学意义（P<0.05）。观察组的口干反应在放疗过程中与对照组比较差异无统计学意义（P>0.05），放疗结束时观察组口干发生率较对照组低，差异有统计学意义（P＜0.05）。观察组所有患者均完成治疗，放疗依从性高于对照组差异有统计学意义（P＜0.05）。结论：早期持续护理干预能有效降低喉癌术后气管切开患者调强放疗期间放疗不良反应发生率，能够保证放射治疗实施的安全性，更重要的是保证患者在最佳时间内坚持全程治疗，提高患者的治疗依从性。

The influence of early continuous nursing intervention on the incidence of radiotherapy adverse reactions and the treatment compliance in tracheotomy patients undergo laryngeal cancer surgery

Objective: To explore the influence of early continuous nursing intervention on the incidence of radiotherapy adverse reactions and the treatment compliance in tracheotomy patients undergo laryngeal cancer surgery. Methods: 72 tracheotomy patients were divided into observation group and control group according to the random number method. 36 patients in observation group were given early continuous nursing intervention on the basis of conventional treatment, while the other 36 patients of control group of accepted conventional care. The incidence of adverse reactions and radiotherapy compliance were compared between the two groups, such as dry mouth, oral mucositis, swallowing pain and white blood cell count during the radiotherapy. Results: The adverse reaction rates of oral mucositis, swallowing pain and leukocyte count in the observation group were lower than those in the control group (P<0.05).There was no statistically significant difference in dry mouth reaction between the observation group and the control group during the radiotherapy process (P>0.05), and the incidence of dry mouth in the observation group was lower than that in the control group at the end of radiotherapy (P<0.05).All patients in the observation group completed treatment, and the compliance with radiotherapy was significantly improved compared with the control group （P<0.05）. Conclusion: Early continuous nursing intervention can effectively reduce intensity-modulated radiation incidence of adverse reactions in tracheotomy patients during radiotherapy, can guarantee the security of radiotherapy implementation. The more important is to ensure that patients in the best time adhere to the full treatment, to improve the therapeutic compliance of patients.