| 氨基糖甙类抗生素抗分枝杆菌作用的研究 |
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| 引用本文： | 李国利,张灵霞. 氨基糖甙类抗生素抗分枝杆菌作用的研究[J]. 中国现代医学杂志, 2007, 17(12): 1507-1509,1513 |
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| 作者姓名： | 李国利 张灵霞 |
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| 作者单位： | 解放军总医院第二附属医院,结核病研究所,北京,100091 |
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| 摘 要： | 目的研究氨基糖甙类抗生素抗分枝杆菌的作用。方法分别测定8种氨基糖甙类抗生素对20种分枝杆菌(包括结核、牛分枝杆菌和18种非结核分枝杆菌)的试管内最低抑菌浓度。结果不同药物显示不同的试管内抗菌作用谱。结论氨基糖甙类抗生素是临床非结核分枝杆菌病治疗可选择的药物。
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| 关 键 词： | 氨基糖甙类抗生素 分枝杆菌 最低抑菌浓度 |
| 文章编号： | 1005-8982（2007）12-1507-03 |
| 收稿时间： | 2006-11-20 |
| 修稿时间： | 2006-11-20 |
Study on effect of aminoglycoside antibiotics against mycobacteria |
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| LI Guo-li,ZHANG Ling-xia. Study on effect of aminoglycoside antibiotics against mycobacteria[J]. China Journal of Modern Medicine, 2007, 17(12): 1507-1509,1513 |
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| Authors: | LI Guo-li ZHANG Ling-xia |
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| Affiliation: | Tuberculosis Research Institute, the Second Affiliated Hospital of General Hospital of PLA, Beijing 10091, P.R.China |
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| Abstract: | [Objective] To evaluate the effect of eight aminoglycoside antibiotics against mycobacteria. [Methods] Minimal inhibitory concentration (MIC) of eight aminoglycoside antibiotics against twenty mycobacteria species in vitro were determined respectively. [Results] The various drugs show different antibacterial effect spectrum in vitro. [Conclusion] Aminoglycoside antibiotics are selection drugs in the treatment of nontuberculosis mycobacterial diseases clinically. |
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| Keywords: | aminoglycoside antibiotics mycobacteria minimal inhibitory concentration |
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