| 活检胃粘膜腺体扩张的组织病理学及免疫组化研究 |
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| 引用本文： | 王仰坤,李建华.活检胃粘膜腺体扩张的组织病理学及免疫组化研究[J].中国肿瘤临床,1993,20(9):656-657. |
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| 作者姓名： | 王仰坤 李建华 |
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| 作者单位： | 解放军第一五○中心医院 (河南洛阳市471031) |
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| 摘 要： | 将134例活检胃粘膜腺体扩张,分为单纯性腺体扩张(81例)和异型性腺体扩张(53例)。胃癌单克隆抗体MG_7抗原表达,在后者有36例(67.9％)呈不同程度的弱阳性,随访2年～12年5例(9.43％)癌变;前者皆为阴性,未见癌变。提示,单纯性腺体扩张是良性病变,异型性腺体扩张为癌前期病变。
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| 关 键 词： | 单克隆抗体 癌前病变 胃肿瘤 活检 |
Histopathologic and Immunohistochemical Study of Glandular Dilatation of Gastric Mucosa Biopsies |
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| Wang Yang-Kun Hospital of PLA,Luoyang.Histopathologic and Immunohistochemical Study of Glandular Dilatation of Gastric Mucosa Biopsies[J].Chinese Journal of Clinical Oncology,1993,20(9):656-657. |
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| Authors: | Wang Yang-Kun Hospital of PLA Luoyang |
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| Institution: | Wang Yang-Kun 105 Hospital of PLA,Luoyang |
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| Abstract: | The glandular dilatation of the gastric mucosa from 134 biopsies was studied histopathologically. The authors divided the dilatation into two types: simple glandular dilatation and dysplastic glandular dilatation. The latter. according to histologic characteristies, might be divided into cystic glandular hyperplasia and adenomatous hyperplasia. Antigen expression tested by monoclonal antibodies MG7 in all the 81 cases of simple glandular dilatation was negative, and positive reaction was obtained in 67. 9% of 53 cases of dysplastic glandular dilatation. The histopathologic and im- munohistochemical features and the follow-up results indicated that simple glandular dilatation was a benign lesion and dys- plastic glandular dilatation was precancerous in nature. |
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| Keywords: | Glandular dilatation Monoclonal antibodies Precancerous lesion |
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