| 全反式维甲酸对急性早幼粒细胞白血病的疗效 |
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| 引用本文： | 夏学鸣,林宝爵.全反式维甲酸对急性早幼粒细胞白血病的疗效[J].中国肿瘤临床,1993,20(6):406-408. |
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| 作者姓名： | 夏学鸣 林宝爵 |
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| 作者单位： | 江苏省血液研究所苏医附一院 (苏州市215006) |
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| 摘 要： | 我们用国产全反式维甲酸治疗急性早幼粒细胞白血病34例,完全缓解率97％。在治疗中,所有病人都先有白细胞数增高现象,但未发生弥散性血管内凝血。主要副作用有皮肤及口唇干燥、头痛等,我们认为维甲酸是当前诱导分化治疗急性早幼粒细胞白血病的一个理想药物。
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| 关 键 词： | 白血病 维甲酸 诱导分化治疗 |
The Therapeutic Effects of AII-trans Retinoic Acid for Acute Promyelocytic Leukemia |
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| Xia Xue-Ming Jiangsu Institute of Hematology,Suzhou.The Therapeutic Effects of AII-trans Retinoic Acid for Acute Promyelocytic Leukemia[J].Chinese Journal of Clinical Oncology,1993,20(6):406-408. |
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| Authors: | Xia Xue-Ming Jiangsu Institute of Hematology Suzhou |
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| Abstract: | Thirty four patients with acute promyelocytic leukemia(APL)were treated with all-trans retinoic acid (RA). The complete remission rate was as high as 97. 1% (33/34). All patients responded with an early high white blood cell count and absence of DIC throughout the treatment. The major side effects included mild dryness of the skin and lip, occasional headache among others.It is suggested that the RA is an effective drug for differentiation induction therapy in APL. |
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| Keywords: | Acute promyelocytic leukemia AII-trans retinoic acid Differentiation induction therapy |
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