精神分裂症患者认知功能评价及其与精神症状的相关性

目的探讨精神分裂症患者的认知功能及其与精神症状的相关性。方法入组31例精神分裂症患者及31例正常对照者,进行持续操作测验(CPT)、威斯康星卡片分类测验(WSCT)、Stroop色词测验、可反复测查的成套神经心理状态评估工具(RBANS)以及阳性与阴性症状量表(PANSS)评定,对心理测查成绩与精神症状指征进行相关性分析。结果精神分裂症患者组与正常对照组相比,除Stroop色词测验中卡片A(字)、B(色)、C(字色)错误数无明显差异外,各项心理测查指标均明显下降(P<0.05)。多项心理测查成绩,包括CPT测验中正确反应时、WSCT测验中随机错误数、Stroop色词测验中字义干扰时和颜色干扰时、RBANS测验总分和即刻记忆分,与PANSS部分症状评分显著相关(P<0.05)。结论精神分裂症患者记忆、注意、执行及言语功能受损。精神分裂症患者部分认知功能与精神症状显著相关。

Evaluation of Cognitive Functions and Its Corelation with Psychiatric Symptoms in Patients with Schizophrenia

Objective To evaluate the cognitive function and its correlation with psychiatric symptoms in patients with schizophrenia.Methods Thirty-one patients with schizophrenia and thirty-one healthy person as control were evaluated by neuropsychological test,such as continuous performance test(CPT),wisconsin card sorting test(WSCT),stroop color-word test and repeatable battery for the assessment of neuropsychological status(RBANS),and the positive and negative syndrome scale(PANSS) in schizophrenic patients.Result...