| 膀胱移行细胞癌EGF,EGFr含量的测定及意义 |
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| 引用本文： | 尚平,周文泉.膀胱移行细胞癌EGF,EGFr含量的测定及意义[J].江苏医药,1997,23(6):383-384. |
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| 作者姓名： | 尚平 周文泉 |
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| 作者单位： | 南京军区南京总医院泌尿外科!210002 |
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| 摘 要： | 用125I标记分析法对25例膀胱移行细胞癌组织和14例正常膀胱组织进行了EGF、EGFr含量测定。表明EGF、EGFr在肿瘤组织中的含量明显高于癌旁正常对照组织（P＜0.05）。肿瘤组织各病理分级组之间EGF、EGFr含量随病理分级增高，有明显增高趋势，但经统计学处理，尚未观察到有显著性差异（P＞0．05）。25例病人术后随访，1年内肿瘤复发的5例患者中，4例肿瘤组织中有EGFr较高水平的表达，表明EGFr与肿瘤复发有一定联系
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| 关 键 词： | 膀胱肿瘤 癌 表皮生长因子受体 |
Expression of Epidermal Growth Factor and Its Receptor in Transitional Cell Carcinoma of Human Urinary Bladder |
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| Shang Ping et al.Expression of Epidermal Growth Factor and Its Receptor in Transitional Cell Carcinoma of Human Urinary Bladder[J].Jiangsu Medical Journal,1997,23(6):383-384. |
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| Authors: | Shang Ping |
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| Abstract: | The expression of epidermal growth factor (EGF) and EGF receptor (EGFr)is at high level insome human tumor tissues. The content of EGF and EGFr were examined by l25I-labeled-EGF binding analysis in25 cases of bladder transitional cell carcinoma and 14 cases of normal bladder mucosa. The relationship betweenthe value of content and prediction of prognosis and relapse of bladder tumor was discussed. |
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| Keywords: | Bladder tumor Carcinoma EGFr |
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