| 载脂蛋白A5与动脉粥样硬化 |
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| 引用本文： | 张志佳,曲伸. 载脂蛋白A5与动脉粥样硬化[J]. 第二军医大学学报, 2012, 33(1): 92-95 |
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| 作者姓名： | 张志佳 曲伸 |
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| 作者单位： | 同济大学医学院附属第十人民医院内分泌科,上海,200072 |
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| 摘 要： | 载脂蛋白A5是一种新发现的主要与HDL相关的载脂蛋白，在临床上它具有明显的降甘油三酯作用，近期发现其可修饰HDL,促进胆固醇的逆转运，可通过多种机制影响动脉粥样硬化进程，具有潜在的抗动脉粥样硬化作用，本文针对载脂蛋白A5的研究及其对动脉粥样硬化的预防及治疗作一综述。
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| 关 键 词： | 载脂蛋白A5；动脉粥样硬化；血脂代谢 |
| 收稿时间： | 2011-06-25 |
| 修稿时间： | 2011-08-25 |
Apolipoprotein A5 and atherosclerosis |
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| ZHANG Zhi-jia and QU Shen. Apolipoprotein A5 and atherosclerosis[J]. Former Academic Journal of Second Military Medical University, 2012, 33(1): 92-95 |
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| Authors: | ZHANG Zhi-jia and QU Shen |
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| Affiliation: | Department of Endocrinology,The 10th People’s Hospital of Shanghai,Tongji University School of Medicine,Shanghai 200072,China |
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| Abstract: | Apolipoprotein A5 is a new kind of apolipoprote which has powerful triglyceride reducing effect and closely associated with HDL remodeling. It is found that Apoa5 can increase cholesteroal reverse transpotation and HDL function by remodeling HDL. This will improve the processes of atherosclerosis in the different ways .Here We briefly review the characteristics of apoa5 and its potenstial protective effect on asthrosclerosis. |
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| Keywords: | Apolipoprotein A5 Atherosclerosis Metabolism of lipides |
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