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| 萝卜秦艽化学成分的研究Ⅰ | |
| 引用本文： | 余振喜,王钢力,边巴次仁,林瑞超.萝卜秦艽化学成分的研究Ⅰ[J].中国中药杂志,2006,31(8):656-658. |
| 作者姓名： | 余振喜 王钢力 边巴次仁 林瑞超 |
| 作者单位： | 1. 北京中医药大学,中药学院,北京,100102;中国药品生物制品检定所,北京,100050 2. 中国药品生物制品检定所,北京,100050 3. 西藏自治区药品检验所,西藏,拉萨,850000 |
| 摘 要： | 目的:研究萝卜秦艽的化学成分。方法:采用大孔树脂、薄层色谱、硅胶柱色谱和制备高效液相色谱进行分离纯化,通过理化方法和波谱数据进行结构鉴定。结果:从95%乙醇提取物大孔树脂40%乙醇洗脱物中分离并鉴定了8个化合物,分别为5-羟基-7-甲氧基-4,6-二甲基-2-苯并呋喃酮(1),4-羟甲基-2-糠醛(2)和6个环烯醚萜苷类化合物6-乙酰基山栀苷甲酯(3),8-乙酰基山栀苷甲酯(4),山栀苷甲酯(5),sesamoside(6),phloyosideⅡ(7)和dehydropentstemoside(8)。结论:所有化合物均为首次从该植物中分得,其中化合物1和3为首次从该属植物中分得。 |
| 关 键 词： | 萝卜秦艽 化学成分 环烯醚萜苷 |
| 文章编号： | 1001-5302（2006）08-0656-03 |
| 收稿时间： | 2005-12-10 |
| 修稿时间： | 2005-12-10 |
Studies on chemical constituents in root of Phlomis medicinalis Ⅰ |
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| YU Zhen-xi,;WANG Gang-li,;BIANBA Ciren,;LIN Rui-chao.Studies on chemical constituents in root of Phlomis medicinalis Ⅰ[J].China Journal of Chinese Materia Medica,2006,31(8):656-658. | |
| Authors: | YU Zhen-xi ;WANG Gang-li ;BIANBA Ciren ;LIN Rui-chao |
| Institution: | 1. College of Chinese Materia Medica, Beijing University of Tradiziond Chinese Medicine, Beijing 100102, China ; 2. National Institute for the Control of Pharmaceutical and Biological Products,Beijing 100050, China; 3. Tibet Institute for Drug Control, Lhasa 850000, China |
| Abstract: | OBJECTIVE: To study the chemical constituents in root of Phlomis medicinalis. METHOD: The compounds were isolated and repeatedly purified on macroporous resin, silica gel column chromatography, TLC and Prep-HPLC and the structures were elucidated by physico-chemical properties and NMR spectra. RESULT: Eight compounds were obtained and elucidated as 5-Hydroxy-7-methoxy-4, 6-dimethylphthalide (1), 4-hydroxymethyl-2-furaldehyde (2) and six iridoid glucosides: 6-O-acetyl-shanzhiside methyl ester (3), 8-O-acetyl-shanzhiside methyl ester (4), shanzhiside methyl ester (5), sesamoside (6), phloyoside II (7) and dehydropentstemoside (8). CONCLUSION: All the compounds were isolated from the plant for the first time and 1 and 3 were obtained from the plants of Phlomis for the first time. |
| Keywords: | Phlomis medicinalis chemical constituents iridoid glucosides |
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