| 几种免疫组化标记物在恶性间皮瘤及肺腺癌诊断中的评价 |
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| 引用本文： | 赵晓光,张惠铭,张丽红,朱桂彬,董艳,董建衡,赵连生.几种免疫组化标记物在恶性间皮瘤及肺腺癌诊断中的评价[J].吉林大学学报(医学版),1992(2). |
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| 作者姓名： | 赵晓光 张惠铭 张丽红 朱桂彬 董艳 董建衡 赵连生 |
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| 作者单位： | 白求恩医科大学基础医学院病理解剖教研室
(赵晓光，张惠铭，张丽红，朱桂彬，董艳)，白求恩医科大学第三临床医学院病理科
(董建衡)，白求恩医科大学第三临床医学院病理科(赵连生) |
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| 摘 要： | 本文使用免疫组织化学方法,对几种标记物在恶性间皮瘤及肺腺癌诊断中所起的作用进行了评价。30例肺腺癌对癌胚抗原(CEA)以及22例肺腺癌对分泌成分(SC)呈现了阳性反应。而所有恶性间皮瘤(8例)对CEA和SC则呈现阴性反应。
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| 关 键 词： | 标记物 恶性间皮瘤 肺腺癌 免疫组织化学 |
EVALUATION OF SEVERAL IMMUNOHISTOCHEMICALMARKERS IN MALIGNANT MESOTHELIOMAAND PULMONARY ADENOCARCINOMA |
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| Zhao Xiaoguang,et al.EVALUATION OF SEVERAL IMMUNOHISTOCHEMICALMARKERS IN MALIGNANT MESOTHELIOMAAND PULMONARY ADENOCARCINOMA[J].Journal of Jilin University: Med Ed,1992(2). |
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| Authors: | Zhao Xiaoguang |
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| Institution: | Department of Pathologa |
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| Abstract: | The role of CEA, keratin, vimentin and secretary component (SC) in the diagnosis of malignant mesothelioma (MM) and pulmonary adenocarcinoma (PA) was evaluated by immunohis-tochemical method. 30 and 22 PA exhibited positive reactions for CEA and SC respectively. In contrast, all MM (8 cases) failed to stain for CEA and SC. 6 MM expressed positive reaction for. while all PA expressed negative reaction for vimentin. 30 PA and 4 MM exhibited positive reaction for keratin. We conclude that use of anti-keratin serum can not provide a help for the differential diagnosis of MM and PA. Positive reaction for CEA and SC favours a diagnosis of PA, whiie positive staining for vimentin but negative for CEA and SC favours the diagnosis of MM. |
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| Keywords: | Markers Malignant mesothelioma Pulmonary adenocarcinoma Immunohistochemistry |
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