| 抗噬菌体鼠疫菌株的发现与研究 |
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| 引用本文： | 谢奉璋,李新兰. 抗噬菌体鼠疫菌株的发现与研究[J]. 地方病通报, 1987, 0(4) |
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| 作者姓名： | 谢奉璋 李新兰 |
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| 作者单位： | 新疆地方病防治研究所 乌鲁木齐(谢奉璋)，新疆地方病防治研究所 乌鲁木齐(李新兰) |
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| 摘 要： | 在天山山地灰旱獭鼠疫自然疫源地中,从病的灰旱獭体内分离出抗鼠疫噬菌体株。该菌株形态呈多形性,菌落不典型,对动物的毒力弱并失去抗源性;但经传代或冷冻干燥保存一段时间后,逐渐失去对鼠疫噬菌体的抗性,与此同时菌落形态转为R型,具有抗原性,对动物的毒力也随之增强。
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| 关 键 词： | 鼠疫噬菌体 抗噬菌体鼠疫菌株 |
DISCOVERY AND STUDY OF A Y. PESTIS STRAIN RESISTANT TO PLAGUE PHAGE |
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| Xie Feng-zhang,Li Xin-lan. DISCOVERY AND STUDY OF A Y. PESTIS STRAIN RESISTANT TO PLAGUE PHAGE[J]. Endemic Diseases Bulletin, 1987, 0(4) |
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| Authors: | Xie Feng-zhang Li Xin-lan |
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| Abstract: | A strain of Ypcsth resistant to plague phage was isolated from an infected grey ma-tmot,Marmota baibacina,in a natural plague focus of Tianshan Mountainous Districts. This strain was found to be multiform in morphology, atypical in colony shape, low virulent for laboratory animals and short of antigenicity; however, it gradually lost its resistance to the bacteriophage after passages or preservation for some time by lyophilization, and at the same time it changed to R type colony, acquired antigenicity, and had increased virulence for animals as well. |
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| Keywords: | plague phage-strain resistant to plague phage-Y.pestis |
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