| 先天性心脏病免疫功能变化及其临床意义 |
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| 引用本文： | 杨林海,苗翠萍,等.先天性心脏病免疫功能变化及其临床意义[J].山西医药杂志,2001,30(2):102-103. |
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| 作者姓名： | 杨林海 苗翠萍 |
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| 作者单位： | [1]山西省儿童医院，030013 [2]榆社县人民医院 |
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| 摘 要： | 目的 了解左向右分流型先天性心脏病 (先心病 )的免疫功能。方法 对 33例先心病患儿免疫球蛋白 ( Ig G、Ig A、Ig M)及 17例患儿 T细胞亚群 ( CD3、CD4、CD8)进行测定。结果 先心病组血中 Ig G、Ig A降低 ,P均 <0 .0 5 ;CD4降低 ,CD8增高 ,CD4/ CD8比值降低 ,P均 <0 .0 5 ;而 Ig M、CD3与对照组比较差异无显著性。结论 先心病患儿有免疫功能低下和免疫调节功能紊乱 ,可能为易患肺炎的原因之一
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| 关 键 词： | 先天性心脏病 免疫功能 免疫球蛋白 T细胞亚群 |
| 修稿时间： | 2000年8月3日 |
Analysis of immune function in children with congenital heart diseases and its clinical significance |
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| Abstract: | Objective To understand the immune function of children with left right shunt congenital heart disease (CHD).Methods The contents of immunoglobulin including IgG,IgA and IgM in serum were detected in 33 cases;the contents of T lymphocyte subset were detected in 17 cases.Results The levels of IgG,IgA,CD4 and CD4/CD8 ratio significantly decreased (P<0 05).The levels of IgM and CD3 had no significant difference in comparison with the normal children.Conclusion Patients with left right shunt CHD had immune dysfunction,which may be one of the reasons for frequent pneumonia. |
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| Keywords: | Congenital heart disease Immune function Immunoglobulin T Lymphocyte subsets |
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