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Transcriptional profiling of depolarization-dependent phenotypic alterations in primary cultures of developing granule neurons

Authors:	Bui Cuong J McGann Alexandra C Middleton Frank A Beaman-Hall Carol M Vallano Mary Lou

Affiliation:	Department of Neurosurgery, SUNY, Upstate Medical University, Syracuse, NY 13210, USA.

Abstract:

Keywords:	VSCCs, voltage-sensitive Ca²⁺ channels NMDA, N-methyl- smallcaps" >d-aspartate NRs, NMDA receptors CaMKK, Ca²⁺ and calmodulin-dependent protein kinase kinase CaMKIV, type IV Ca²⁺ and calmodulin-dependent protein kinase GCs, cerebellar granule cells IP₃R, inositol trisphosphate receptors CB1, type 1 cannabinoid receptors fc, final concentration DIV, days in vitro Sst, somatostatin KCC2, potassium-chloride co-transporter Ppp1r1a, phosphatase 1A Plagl1, pleiomorphic adenoma gene-like 1 BDNF, brain-derived neurotrophic factor Oxr1, oxidation resistance 1 NT3, neurotrophin 3 Epac2, cAMP-regulated guanine nucleotide exchange factor Sstr2, somatostatin receptor 2 NPTX, neuronal pentraxin EGL, external granular layer IGL, internal granular layer P8, postnatal day 8 MTT, 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide DMSO, dimethyl sulfoxide GCOS, GeneChip Operating System
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