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| 不同钙制剂对废用性骨质疏松大鼠几项指标的影响 | |
| 引用本文： | 田玉慧,李延兰,李万里,张永喜,高倩,刘玉府.不同钙制剂对废用性骨质疏松大鼠几项指标的影响[J].中国公共卫生,2001,17(11):1022-1023. |
| 作者姓名： | 田玉慧 李延兰 李万里 张永喜 高倩 刘玉府 |
| 作者单位： | 1. 新乡医学院预防医学教研室, 2. 新乡医学院细胞生物教研室 3. 新乡医学院 |
| 基金项目： | 河南省自然科学基金项目(964021500) |
| 摘 要： | 目的：探讨不同钙对废用性骨质收松大鼠血清无机盐，肝MDA，AKP的影响。方法：健康SD大鼠50只，分为5组，雌雄各半，2－5组复制骨质疏松动物模型，1－2组喂普通饲料，3－5组喂补钙实验饲料，2月后测其骨密度及血钙，锌，铜，AKP，肝MDA，结果：废用性骨质疏松组的血钙，血铜，铜／锌，肝MDA，AKP明显增高而血锌明显降低。补钙组骨密度及骨矿物含量明显高于未补钙实验组，肝MDA，血AKP显著降低。结论：补钙可增加废用性骨骼的骨密度，并影响肝MDA，血AKP含量。 |
| 关 键 词： | 骨密度 钙 MDA AKP 废有性骨质疏松 血锌 血铜 钙制剂 |
| 文章编号： | 1001-0580(2001)11-1022-02 |
Effects of Different Calcium on Several Parameters of Disuse Os teoporosis in Rats |
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| TIAN Yu hui,et al..Effects of Different Calcium on Several Parameters of Disuse Os teoporosis in Rats[J].Chinese Journal of Public Health,2001,17(11):1022-1023. | |
| Authors: | TIAN Yu hui |
| Institution: | TIAN Yu hui,et al.Department of Preventive Medicine of Xinxiang Medical College |
| Abstract: | Objective To study the effect of different Ca on serum calcium,zinc,copper,AKP and MDA of disuse osteoporosis.Methods Fifty two-month old healthy SD rats were randomly divided into 5 groups,half male and half female.Group 2,3,4 and 5 were reproduced with patterns of animal osteoporosis.The diet in group 1 and group 2 was the basic diet,while the groups 3,4,5 experiment diets were supplemented with different Ca.The BMD,BMC ,serum calcium,zinc ,copper,AKP and MDA were measured two months later.Results The serum Ca?Cu?Cu/Zn?MDA and AKP in disuse osteoporosis group were higher than no disuse osteoporosis group,but Zn was lower.Ca supplement could increase the BMD and decrease the MDA?AKP of disuse osteoporosis in rats.Conclusion Ca supplement could increase the BMD,AKP,MDA of disuse osteoporosis in rats. |
| Keywords: | bone mineral density Ca MDA AKP |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |