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Aeromonas aquariorum septicemia and enterocolitis in a cirrhotic patient
Authors:Chi-Jung Wu  Pei-Jane Tsai  Po-Lin Chen  I-Chien Wu  Yu-Tzu Lin  Yi-Hsuan Chen  Li-Rong Wang  Wen-Chien Ko
Affiliation:1. Department of Graduate Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan;2. Department of Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwan;3. National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Zhunan Township, Miaoli County, Taiwan;4. Department of Medical Laboratory Science and Biotechnology, College of Medicine, National Cheng Kung University, Tainan, Taiwan;5. Infectious Disease and Signaling Research Center, College of Medicine, National Cheng Kung University, Tainan, Taiwan;6. Institute of Population Health Sciences, National Health Research Institutes, Zhunan Township, Miaoli County, Taiwan;g Center for Infection Control, National Cheng Kung University Hospital, Tainan, Taiwan;h Department of Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan
Abstract:Aeromonas aquariorum is a recently described Aeromonas species. We present a cirrhotic patient with septicemia and bloody diarrhea in whom A. aquariorum was isolated from the blood and stool. The species identification was based on sequence analysis of the partial rpoB and rpoD genes. The A. aquariorum isolates carried genes encoding hemolysin, aerolysin, and the cytotonic enterotoxin Alt. Significant A. aquariorum–induced cytotoxicity in intestinal epithelial cells was also demonstrated.
Keywords:Aeromonas aquariorum   Septicemia   Enterocolitis   Cytotoxicity
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