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不同方法提取淫羊藿苷的正交试验研究
引用本文:杨帆,钟桂雄,赵洪普,林春燕,温晓清,何小玲.不同方法提取淫羊藿苷的正交试验研究[J].中国药房,2005,16(6):416-418.
作者姓名:杨帆  钟桂雄  赵洪普  林春燕  温晓清  何小玲
作者单位:1. 广东药学院药科学院,广州市,510224
2. 丽珠集团利民制药厂,韶关市,512028
3. 广东省中医院,广州市,510000
4. 广东药学院药学系,2000级学生,广州市,510224
基金项目:广东省中医药管理局科研项目
摘    要:目的 :筛选淫羊藿苷最佳提取方法和提取工艺条件。方法 :分别采用乙醇回流法和乙醇超声波法提取淫羊藿苷 ,并以淫羊藿苷的含量为指标 ,对提取工艺中的乙醇用量、乙醇浓度、提取时间、提取次数等因素进行考察。结果与结论 :乙醇回流法对淫羊藿苷的提取效果优于乙醇超声法 ;乙醇回流法提取淫羊藿苷的最佳提取工艺条件是用8倍药材量的60 %乙醇提取淫羊藿3次 ,每次40min。

关 键 词:淫羊藿苷  提取工艺  回流法  超声波法
文章编号:1001-0408(2005)06-0416-03
修稿时间:2004年8月23日

Orthogonal Design Experiment on the Extracting of Icariin by Different Means
YANG Fan,ZHONG Guixiong,ZHAO Hongpu,LIN Chunyan,WEN Xiaoqing,HE Xiaoling.Orthogonal Design Experiment on the Extracting of Icariin by Different Means[J].China Pharmacy,2005,16(6):416-418.
Authors:YANG Fan  ZHONG Guixiong  ZHAO Hongpu  LIN Chunyan  WEN Xiaoqing  HE Xiaoling
Abstract:OBJECTIVE:To optimize the extraction and preparation technics of icariin by orthogonal design.METHODS:The icariin was extracted by the ethanol reflux and the ethanol ultrasonic extracting process respectively;the quantity and concentration of ethanol,extracting time and extracting times were investigated with the content of the icariin as a indicator.RESULTS & CONCLUSION:The ethanol refluxing process is better than the ethanol ultrasonic process in the extraction of icariin.The most optimistic condition of extracting of icariin in ethanol refluxing extracting process was as follows:the crude drug was extracted for 3 times(40min/time)by using 60% ethanol,which is 8 times of the amount of the crude drug.
Keywords:Icariin  Extraction technics  Refluxing process  Ultrasonic process
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