妊娠梅毒母婴阻断治疗效果及护理

目的探讨母婴阻断治疗及护理对妊娠梅毒患者的影响。方法采用回顾性方法对住院分娩的108例妊娠梅毒患者及婴儿资料进行随访分析，比较治疗与非治疗患者妊娠结局及新生儿预后情况。结果108例妊娠梅毒孕妇分娩孕周平均（38．22±1．795）周，早产5例占4．63％，治疗组足月产率98．51％高于未治疗组的90．24％，但差异无统计学意义（x2=2．29，P〉0．05）；治疗组孕妇分娩的先天梅毒患儿为4．48％少于未治疗组的29．27％，差异有统计学意义（x2=13．07，P〈0．01）；孕妇在孕期未行正规治疗或未治疗者，及新生儿诊为先天梅毒者，立即进行驱梅治疗，79．63％血浆反应素环状卡片试验（RPR）在1岁内全部转阴，79．41％梅毒螺旋体颗粒凝集试验（TPPA）在18个月内转阴，其余均为2～3年内转阴。结论加强妊娠梅毒孕妇的孕期保健和管理工作，做好宣传教育和婴儿的随访监测工作，对预防先天性梅毒及保证婴儿的健康成长有重要意义。

Effect of blocking of maternal-fetal transmission of syphilis on pregnancy and nursing

Objective To explore blocking of maternal-fetal transmission of syphilis in pregnancy and nursing care. Methods By retrospectively analyzing 108 cases, collected from January 2005 to October 2007, of blocking maternal-fetal transmission data among pregnant women infected with syphilis. Pregnancy outcome and prognosis status were compared between those under therapy and those were not. Results Average gestational week was（38.22 ±1. 795 ） weeks, 5 patients had premature delivery, accounting for 4.63% ; Full- term rate in treatment group was 98.51% and 90. 24% in untreatment group, and the difference was not statistically significant （X2 =2.29 ,P 〉 0. 05 ） ; Infants with congenital syphilis in treatment group was 4.48% and less than 29.27% in the untreatment group, and the difference was significant （ X2 = 13.07, P 〈 0. 01 ） ; Those pregnant women, who did not receive standard treatment and the infant was diagnosed as congenital syphilis, were treated with anti-syphilitic therapy, and 79.63% of RPR was negative within one year, 79.41% of TPPA was negative within 18 months, and all the other turned negative in 2 -3 years. Conclusions Reinforcing health care and supervision during gestation and evaluating pregnant women syphilis infection and treatment condition in time could prevent them from cross-infection and insure the healthy growth of children.