Late-onset seizures and risk of subsequent stroke: A systematic review |
| |
| Affiliation: | 1. Department of Neurological and Movement Sciences, Section of Clinical Neurology, University of Verona, Italy;2. Division of Neurology, Franz Tappeiner Hospital, Merano, Italy;3. Department of Neurology, Christian Doppler Klinik, Paracelsus Medical University, Salzburg, Austria;1. Cardiology Division, Gachon University Gil Medical Center, Incheon, Korea;2. Cardiology Division, Korea University Anam Hospital, Seoul, Korea;1. Children''s Hospital of Pittsburgh, Division of Child Neurology, 4401 Penn Avenue, Pittsburgh, PA 15224, USA;2. Semel Institute for Neuroscience and Human Behavior, UCLA, 760 Westwood Plaza, Rm. 48-226, Los Angeles, CA 90095-1759, USA;3. Department of Neurology, School of Medicine and Public Health, Matthews Neuropsychology Lab, 7223 UW Medical Foundation Centennial Building, 1685 Highland Ave, Madison, WI 53705-2281, USA |
| |
| Abstract: | Otherwise unexplained late-onset seizures, conventionally defined as epileptic seizures occurring in subjects older than 60 years and in the absence of disorders known to increase the risk of developing epilepsy, have been assumed to be, in most cases, of cerebrovascular origin. We systematically searched the literature to identify the evidence supporting the association between otherwise unexplained late-onset seizures/epilepsy and the risk of subsequent stroke. Most data from the literature indicate that cerebrovascular disease often underlies otherwise unexplained late-onset seizures/epilepsy. Patients presenting with seizures occurring for the very first time in late life and without clinically overt cerebrovascular disease should be considered as at increased risk of stroke. Consequently, these patients should be screened for the presence of vascular risk factors and treated accordingly. Such measures may greatly contribute to prevent strokes in these patients. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
