Metastasis to the nasal cavity from primary rectal adenocarcinoma |
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| Authors: | Carlos Conill Mauricio Vargas Izaskun Valduvieco Pedro L. Fernández Antonio Cardesa Sebastián Capurro |
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| Affiliation: | (1) Division of Gastroenterology, Department of Internal Medicine, Mackay Memorial Hospital, Mackay Medicine, Nursing and Management College, No. 92, Sec. 2, Chung Shan North Road, Taipei, Taiwan;(2) National Institute of Cancer Research, National Health Research Institutes, Taipei, Taiwan;(3) Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan;(4) Department of Otolaryngology, Mackay Memorial Hospital, Taipei, Taiwan;(5) Department of Radiology, Mackay Memorial Hospital, Taipei, Taiwan;(6) Department of Pathology, Mackay Memorial Hospital, Taipei, Taiwan; |
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| Abstract: | We describe a rare case of metastasis to the paranasal sinuses. The lesion had an immunohistochemical (positivity for cytokeratin 20, negativity for cytokeratin 7, overexpression of p53) and in situ hybridisation profile (neither lesions showed deletion for p53) consistent with metastasis from the earlier rectal adenocarcinoma. The correct typification of intestinal-type neoplasms requires a combination of morphological, immunohistochemical and, sometimes, molecular analysis. |
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| Keywords: | Nasal cavity Paranasal sinuses Metastasis Rectal adenocarcinoma p53 In situ hybridisation |
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