A comparison of missing data methods for hypothesis tests of the treatment effect in substance abuse clinical trials: a Monte-Carlo simulation study期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

A comparison of missing data methods for hypothesis tests of the treatment effect in substance abuse clinical trials: a Monte-Carlo simulation study

Authors:	Sarra L Hedden Robert F Woolson Robert J Malcolm

Affiliation:	(1) Department of Biostatistics, Bioinformatics and Epidemiology, Medical University of South Carolina, 135 Cannon Place, 29425 Charleston, SC, USA;(2) Department of Psychiatry and Behavioral Research, Medical University of South Carolina, 67 President Street, 29425 Charleston, SC, USA;(3) Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, 2213 McElderry St., Suite 400, 21205 Baltimore, MD, USA

Abstract:	Background Missing data due to attrition are rampant in substance abuse clinical trials. However, missing data are often ignored in the presentation of substance abuse clinical trials. This paper demonstrates missing data methods which may be used for hypothesis testing.

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