| 自体骨髓移植复合人工骨治疗骨缺损 |
| |
| 引用本文： | 林坚平,宋世锋,黎早敏,陈剑飞,吴多能,肖海涛.自体骨髓移植复合人工骨治疗骨缺损[J].中国组织工程研究与临床康复,2011,15(26). |
| |
| 作者姓名： | 林坚平 宋世锋 黎早敏 陈剑飞 吴多能 肖海涛 |
| |
| 作者单位： | 河南省人民医院创伤骨科,海南省海口市,570311 |
| |
| 摘 要： | 背景:到目前为止,国内人工骨联合自体骨髓移植治疗新鲜骨折、骨缺损方面的基础与临床研究尚未见报道。目的:分析自体骨髓移植复合人工骨修复四肢粉碎性骨折骨缺损的作用途径。方法:42例四肢骨缺损患者按治疗方法分为3组,均采用内固定方法修复骨折骨缺损。复合组采用自体骨髓移植复合人工骨,人工骨移植组仅作单纯的人工骨移植,自体骨髓移植组仅将单纯的自体骨髓注射入骨缺损处。所有患者均行骨特异性碱性磷酸酶活性检测和影像学随访,观察骨痂形成及骨折愈合情况。结果与结论:在内固定后第3,4,6周,复合组伤肢骨痂形成率、骨特异性碱性磷酸酶活性均显著高于人工骨移植组及自体骨髓移植组(P<0.01)。提示自体骨髓移植复合人工骨较单纯的人工骨移植或自体骨髓移植更能促进早期骨痂反应,加速骨折后骨缺损愈合,缩短骨愈合时间及住院时间。
|
| 关 键 词： | 骨折 骨缺损 骨髓移植 人工骨 骨折愈合 |
Treatment of bone defects with autologous bone marrow transplantation combined with bone allograft |
| |
| Lin Jian-ping,Song Shi-feng,Li Zao-min,Chen Jian-fei,Wu Duo-neng,Xiao Hai-tao.Treatment of bone defects with autologous bone marrow transplantation combined with bone allograft[J].Journal of Clinical Rehabilitative Tissue Engineering Research,2011,15(26). |
| |
| Authors: | Lin Jian-ping Song Shi-feng Li Zao-min Chen Jian-fei Wu Duo-neng Xiao Hai-tao |
| |
| Institution: | Lin Jian-ping,Song Shi-feng,Li Zao-min,Chen Jian-fei,Wu Duo-neng,Xiao Hai-tao Department of Orthopedic Trauma,People's Hospital of Hainan Province,Haikou 570311,Hainan Province,China |
| |
| Abstract: | BACKGROUND:Up to now,there are no reports about autologous bone marrow transplantation combined with bone allograft for fresh bone fractures and bone defects in China.OBJECTIVE:To investigate the mechanism of autologous bone marrow transplantation combined with bone allograft in the treatment of limb fractures.METHODS:Forty-two cases of limb fractures were randomly divided into three groups:combination group,bone allograft and autologous bone marrow transplantation groups.All patients underwent bone specifi... |
| |
| Keywords: | |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
