| 胸苷磷酸化酶及血管内皮生长因子在胃腺癌组织中的表达及其临床意义 |
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| 引用本文： | 夏传生,李娜萍,李明显,李丹. 胸苷磷酸化酶及血管内皮生长因子在胃腺癌组织中的表达及其临床意义[J]. 华中科技大学学报(医学版), 2011, 40(3): 343-346,353. DOI: 10.3870/j.issn.1672-0741.2011.03.022 |
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| 作者姓名： | 夏传生 李娜萍 李明显 李丹 |
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| 作者单位： | 1. 中国人民解放军第457医院普通外科,武汉,430012
2. 华中科技大学同济医学院附属同济医院病理研究所,武汉,430030 |
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| 基金项目： | 国家自然科学基金资助项目 |
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| 摘 要： | 目的 检测胸苷磷酸化酶(TP)及血管内皮生长因子(VEGF)在胃腺癌组织中的表达及其与患者年龄、性别、肿瘤大小、分化程度、浸润深度及淋巴结转移的关系,分析TP、VEGF的表达及其临床意义.方法 采用免疫组织化学EnVision TM法检测125例胃癌组织中TP、VEGF的表达,以30例肿瘤切缘正常胃黏膜组织作为对照.结...
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| 关 键 词： | 胃腺癌 胸苷磷酸化酶 血管内皮生长因子 预后 |
Expression of TP and VEGF in Gastric Adenocarcinoma and Its Correlation with Clinicopathological Features |
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| Xia Chuansheng,Li Naping,Li Mingxian et al. Expression of TP and VEGF in Gastric Adenocarcinoma and Its Correlation with Clinicopathological Features[J]. Journal of Huazhong University of Science and Technology(Health Sciences), 2011, 40(3): 343-346,353. DOI: 10.3870/j.issn.1672-0741.2011.03.022 |
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| Authors: | Xia Chuansheng Li Naping Li Mingxian et al |
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| Affiliation: | Xia Chuansheng1,Li Naping2,Li Mingxian2 et al1Department of General Surgery,No.457th Hospital of PLA,Wuhan 430012,China2Department of Pathology,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China |
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| Abstract: | Objective To investigate the expression of thymidine phosphorylase(TP)and vascular endothelial growth factor(VEGF)in gastric adenocarcinoma and its relationship with age,sex,tumor size,degree of differentiation and lymph node metastasis.Methods Immunohistochemistry was used to detect the expression of TP and VEGF in 125 cases of gastric adenocarcinoma and 30 cases of normal gastric mucosa of tumor incisal edge.Results TP and VEGF were negatively expressed in normal gastric mucosa,but TP expression was detec... |
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| Keywords: | gastric adenocarcinoma thymidine phosphorylase vascular endothelial cell growth factor prognosis |
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