| 兔动脉粥样硬化斑块内VSMCs凋亡与RANTES水平的相关性研究 |
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| 引用本文： | 丁艳萍,彭昱东,周恒,周心涛,李海禹,曾秋棠.兔动脉粥样硬化斑块内VSMCs凋亡与RANTES水平的相关性研究[J].华中科技大学学报(医学版),2011,40(3):274-278,295. |
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| 作者姓名： | 丁艳萍 彭昱东 周恒 周心涛 李海禹 曾秋棠 |
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| 作者单位： | 华中科技大学同济医学院附属协和医院心血管病研究所心内科,武汉,430022 |
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| 基金项目： | 国家自然科学基金资助项目 |
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| 摘 要： | 目的 研究血浆和斑块局部受激活后调节性正常T细胞表达和分泌因子(regulated on activated normal T cell expressed and secreted factor,RANTES)表达水平与兔动脉粥样硬化斑块内血管平滑肌细胞(vascular smooth muscle cells,VS...
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| 关 键 词： | 血管平滑肌细胞 细胞凋亡 受激活后调节性正常T细胞表达和分泌因子 易损动脉粥样硬化斑块 |
Correlations between Expression of RANTES and Apoptosis of VSMCs in Atherosclerotic Rabbits |
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| Ding Yanping,Peng Yudong,Zhou Heng et alInstitute of Cardiology,Union Hospital,Tongji Medical College,HuazhongUniversity of Science , Technology,Wuhan ,China.Correlations between Expression of RANTES and Apoptosis of VSMCs in Atherosclerotic Rabbits[J].Journal of Huazhong University of Science and Technology(Health Sciences),2011,40(3):274-278,295. |
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| Authors: | Ding Yanping Peng Yudong Zhou Heng Institute of Cardiology Union Hospital Tongji Medical College HuazhongUniversity of Science Technology Wuhan China |
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| Institution: | Ding Yanping,Peng Yudong,Zhou Heng et alInstitute of Cardiology,Union Hospital,Tongji Medical College,HuazhongUniversity of Science and Technology,Wuhan 430022,China |
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| Abstract: | Objective To study the correlations between the expression of regulated on activated normal T cell expressed and secreted factor(RANTES)and apoptosis of vascular smooth muscle cells(VSMCs)in atherosclerotic rabbits.Methods Forty male rabbits were divided into four groups randomly:(1)blank group(n=10)and control group(n=10):receiving a standard diet for 16 weeks;(2)AS group(n=10)and VAP group(n=10):receiving a high-cholesterol diet(1% cholesterol,5% lard in rabbit food)for 16 weeks.Blank and AS groups were t... |
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| Keywords: | vascular smooth muscle cells apoptosis regulated on activated normal T cell expressed and secreted factor vulnerable atherosclerotic plaque |
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