| Notch3在卵巢上皮性癌中的表达及临床意义 |
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| 引用本文： | 王中显,陶涛,周志刚,周婷,卢运萍,王世宣. Notch3在卵巢上皮性癌中的表达及临床意义[J]. 华中科技大学学报(医学版), 2011, 40(3): 264-267. DOI: 10.3870/j.issn.1672-0741.2011.03.004 |
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| 作者姓名： | 王中显 陶涛 周志刚 周婷 卢运萍 王世宣 |
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| 作者单位： | 华中科技大学同济医学院附属同济医院妇产科,武汉,430030 |
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| 基金项目： | 国家重点基础研究发展计划资助项目 |
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| 摘 要： | 目的 探讨卵巢上皮性癌组织中Notch3的表达与卵巢癌血管生成以及临床病理特征的关系.方法 应用免疫组织化学SP法检测91例卵巢肿瘤组织中Notch3的表达和CD34标记的微血管密度(MVD),结合临床病理特征进行综合分析.结果 在恶性和交界性卵巢肿瘤组织中Notch3阳性率及MVD计数均显著高于正常卵巢和良性卵巢肿瘤...
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| 关 键 词： | 卵巢肿瘤 Notch3 微血管密度 血管生成 |
Expression of Notch3 in Ovarian Carcinoma and Its Relationship with Angiogenesis |
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| Wang Zhongxian,Tao Tao,Zhou Zhigang et al. Expression of Notch3 in Ovarian Carcinoma and Its Relationship with Angiogenesis[J]. Journal of Huazhong University of Science and Technology(Health Sciences), 2011, 40(3): 264-267. DOI: 10.3870/j.issn.1672-0741.2011.03.004 |
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| Authors: | Wang Zhongxian Tao Tao Zhou Zhigang et al |
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| Affiliation: | Wang Zhongxian,Tao Tao,Zhou Zhigang et alDepartment of Obstetrics and Gynecology,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China |
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| Abstract: | Objective To investigate the expression of Notch3 and its relationship with angiogenesis in ovarian epithelial carcinoma and its relevance to clinicopathologic features.Methods The expression levels of Notch3 and CD34 were detected by using immunohistochemistry SP method in 91 ovarian tumor specimens.The microvessel density(MVD)was determined with CD34 immunostaining of microvascular endothelial cells.Statistical analysis was performed using the software SPSS(version 12.0).Results Notch3 positive rate and M... |
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| Keywords: | Notch3 |
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